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Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
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Relationship Between Brachial-Ankle Pulse Wave Velocity and Incident Hypertension According to 2017 ACC/AHA High

Seung Jae Lee1, Alberto Avolio2, Dae Chul Seo1

  • 1Division of Cardiology Department of Internal Medicine Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine Seoul Republic of Korea.

Journal of the American Heart Association
|August 16, 2019
PubMed

Insights

Arterial stiffness, measured by brachial-ankle pulse wave velocity (baPWV), predicts new-onset hypertension. Higher baPWV indicates an increased risk for developing high blood pressure, even under updated guidelines.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Vascular Medicine

Background:

  • Arterial stiffness is a known predictor of cardiovascular events and incident hypertension.
  • The predictive value of brachial-ankle pulse wave velocity (baPWV) for incident hypertension, using the 2017 ACC/AHA guidelines, remains unestablished.

Purpose of the Study:

  • To investigate whether baPWV measurements, as an indicator of arterial stiffness, can predict incident hypertension based on the 2017 ACC/AHA High Blood Pressure Guidelines.

Main Methods:

  • A cohort study of 10,360 Korean adults who underwent baPWV examination.
  • Hypertension defined as 130/80 mmHg per 2017 ACC/AHA Guidelines.
  • Cox proportional hazard analysis used to assess hypertension risk across baPWV quartiles.

Main Results:

  • During a median follow-up of 2.17 years, 19.3% of subjects developed hypertension.
  • The highest baPWV quartile group showed a significantly increased risk of hypertension compared to the lowest quartile (HR 1.64 in men, 12.36 in women).
  • This association remained significant after adjusting for confounding factors.

Conclusions:

  • Arterial stiffness, assessed by baPWV, is associated with incident hypertension under the 2017 ACC/AHA Guidelines.
  • baPWV serves as a valuable, independent predictor of developing hypertension in a relatively healthy population.

Keywords:
arterial stiffnessatherosclerosisbrachial‐ankle pulse wave velocityhypertension

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