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Ex Vivo Oculomotor Slice Culture from Embryonic GFP-Expressing Mice for Time-Lapse Imaging of Oculomotor Nerve Outgrowth
Published on: July 16, 2019
Oculomotor schwannoma causing a progressive complete third-nerve palsy.
Emily Bentley1, Ronak Ved1, Caroline Hayhurst1
1Department of Neurosurgery, Cardiff and Vale University Health Board, Cardiff, UK.
Oculomotor nerve schwannoma, a rare cause of double vision (diplopia), was diagnosed in a 69-year-old woman. This study discusses the diagnosis and management of this uncommon condition.
Area of Science:
- Neuro-oncology
- Ophthalmology
- Neurology
Background:
- Oculomotor nerve palsy, characterized by double vision (diplopia), can stem from various causes.
- Schwannomas, typically benign nerve sheath tumors, can rarely affect the oculomotor nerve.
Observation:
- A 69-year-old woman presented with an 8-month history of diplopia and right third-nerve palsy.
- Head MRI revealed a 5.8 mm nodular lesion in the suprasellar cistern with gadolinium enhancement.
- The lesion showed no interval growth over a 3-month follow-up period.
Findings:
- The clinical presentation and MRI findings were consistent with an oculomotor nerve schwannoma.
- Oculomotor schwannomas are an uncommon etiology for third-nerve palsy.
Implications:
- This case highlights the importance of considering rare diagnoses like oculomotor nerve schwannoma in patients with third-nerve palsy.
- Understanding the presentation and management of these tumors is crucial for effective patient care.
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