Graphene-based 3D scaffolds in tissue engineering: fabrication, applications, and future scope in liver tissue
Renu Geetha Bai1, Kasturi Muthoosamy1, Sivakumar Manickam1
1Nanotechnology and Advanced Materials (NATAM), Faculty of Science and Engineering, University of Nottingham Malaysia, Semenyih, Selangor, 43500, Malaysia.
International Journal of Nanomedicine
|August 16, 2019
Summary
Graphene nanomaterials offer excellent properties for tissue engineering scaffolds, supporting cell differentiation and mimicking in vivo conditions. This review explores their potential in regenerative therapy and organ repair.
Area of Science:
- Biomaterials Science
- Regenerative Medicine
- Nanotechnology
Background:
- Tissue engineering aims to repair or replace damaged tissues and organs.
- Graphene-based materials possess unique properties making them suitable for biomedical applications.
- Previous research highlights graphene's potential in various tissue scaffolds.
Purpose of the Study:
- To review the application of graphene-based nanomaterials in tissue engineering.
- To discuss the properties of graphene that make it ideal for scaffold development.
- To explore the potential of graphene in regenerative therapy, including liver tissue engineering.
Main Methods:
- Literature review of studies on graphene in 2D and 3D tissue culture scaffolds.
- Analysis of graphene's physical, chemical, optical, and biological properties relevant to tissue engineering.
- Examination of graphene's role in mimicking in vivo environments and promoting stem cell differentiation.
Main Results:
- Graphene-based materials effectively mimic in vivo environments for tissue scaffolds.
- Properties like porosity, large surface area, mechanical strength, and conductivity are advantageous.
- Graphene scaffolds support stem cell differentiation into specific cell types.
- Graphene shows promise in liver tissue engineering applications.
Conclusions:
- Graphene-based nanomaterials are highly promising for advanced tissue engineering scaffolds.
- Their unique properties facilitate the creation of effective microenvironments for tissue regeneration.
- Graphene holds significant potential for future regenerative medicine and therapeutic applications.
More Related Videos
12:28Melt Electrospinning Writing of Three-dimensional Poly(ε-caprolactone) Scaffolds with Controllable Morphologies for Tissue Engineering Applications
Published on: December 23, 2017
15.7K
07:14Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering
Published on: July 27, 2022
4.1K
Related Concept Videos
00:49What is Genetic Engineering?
79.7K
Overview
79.7K
01:10Heat Engines
3.6K
A heat engine is a device used to extract heat from a source and then convert it into mechanical work used for various applications. For example, a steam engine on an old-style train can produce the work needed for driving the train.
Whenever we consider heat engines (and associated devices such as refrigerators and heat pumps), we do not use the standard sign convention for heat and work. For convenience, we assume that the symbols Qh, Qc, and W represent only the amounts of heat transferred...
Whenever we consider heat engines (and associated devices such as refrigerators and heat pumps), we do not use the standard sign convention for heat and work. For convenience, we assume that the symbols Qh, Qc, and W represent only the amounts of heat transferred...
3.6K
01:20Internal Combustion Engine
2.6K
The internal combustion engine is a heat engine that uses the byproducts of combustion as the working fluid instead of using a heat transfer medium to transfer heat. The combustion is done in a way that produces high-pressure combustion products that can be expanded through a turbine or piston to create work. Internal combustion engines can again be categorized into three kinds: (1) spark ignition gasoline engines, most commonly used in automobiles, (2) compression ignition diesel engines that...
2.6K
01:17The Scope of Physics
52.2K
Physics is concerned with the interactions of energy, matter, space, and time, in order to discover the underlying mechanisms that underpin all phenomena. The word "physics" comes from the Greek word "phúsis", which means nature. Physics seeks to comprehend the natural world around us at its most fundamental level. It emphasizes the use of quantitative laws to do this, which could be valuable in other fields that want to push the performance boundaries of present...
52.2K
01:18Tissues
84.7K
Cells with similar structure and function are grouped into tissues. A group of tissues with a specialized function is called an organ. There are four main types of tissue in vertebrates: epithelial, connective, muscle, and nervous.
84.7K
01:25Tissues
63.5K
Tissues are a group of cells that share a common embryonic origin. Microscopic observation reveals that the cells in a tissue share morphological features and are arranged in an orderly pattern to perform specific functions. From an evolutionary perspective, tissues appear in more complex organisms. Although there are many types of cells in the human body, they are organized into four broad categories of tissues: epithelial, connective, muscle, and nervous. Each of these categories is...
63.5K