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In Praise of Remarkably Powerful Centamolecular Therapeutic Agents
Nicholas A Meanwell1, William R Ewing1
1Department of Discovery Chemistry, Bristol-Myers Squibb Research and Development, PO Box 4000, Princeton, New Jersey 08543-4000, United States.
Abstract:
While biological medications have addressed many important and challenging therapeutic targets, the pharmacopeia is still dominated by centamolecules. In this Viewpoint, we illustrate the impact of centamolecule drugs on mortality and morbidity due to chronic viral infections and present select examples from other disease areas that highlight some of their remarkably powerful biochemical effects.
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