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Updated: Jan 20, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
[Challenges in the diagnosis of cartilage tumors : Morphological spectrum and molecular markers]
1Sektion für Translationale Pathologie, Gerhard-Domagk-Institut für Pathologie, Universitätsklinikum Münster, Albert-Schweitzer-Campus 1, D17, 48149, Münster, Deutschland. wolfgang.hartmann@ukmuenster.de.
Abstract:
The morphological and clinico-biological spectrum of chondrogenic tumours is wide. Given the diversity of therapeutic approaches, the correctness of the histological diagnosis is of major importance. The aim of this review is to provide insights into the challenges and limitations of diagnostic approaches restricted to morphology and to underscore the importance of an interdisciplinary dialogue between surgeons, radiologists and pathologists. Beyond this, the value of molecular analyses introduced in bone tumor diagnostics in recent years is discussed.
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