Related Experiment Video
Updated: Aug 3, 2026
Doppler Optical Coherence Tomography of Retinal Circulation
Published on: September 18, 2012
Comparison of Optical Coherence Tomography Angiography Findings in Patients with Behçet's Disease and Healthy
Semra Koca1, Duru Onan2, Defne Kalaycı3
1Ophthalmologist, Department of Ophthalmology, Denizli State Hospital , Denizli, Turkey.
Purpose:
To investigate optical coherence tomography angiography (OCTA) findings in patients with Behçet's disease (BD).
Methods:
Ninety-four eyes of 49 patients with BD and 53 eyes of 53 healthy subjects were included. Vascular density (VD), foveal avascular zone (FAZ) area, perifoveal capillary hypoperfusion, perifoveal capillary network disorganization, and FAZ irregularity were analyzed.
Results:
OCTA revealed retinal VD reduction and higher perifoveal capillary hypoperfusion, perifoveal capillary network disorganization and FAZ irregularity in ocular Behçet's compared to nonocular Behçet's (p = .000). However, compared to normal eyes, there was no difference between any OCTA measurements in nonocular BD patients. The mean area of FAZ was not different in any group (p = .266). In ocular Behçet, visual acuity was inversely correlated with FAZ area and FAZ irregularity.
Conclusion:
Retinal VD decreases and perifoveal microvascular network changes in ocular Behçet's. FAZ irregularity may be a more valuable marker than FAZ area for indicating ocular involvement.
