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Alternate subunit assembly diversifies the function of a bacterial toxin.

Casey C Fowler1,2, Gabrielle Stack1, Xuyao Jiao1

  • 1Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, 06536, USA.

Nature Communications
|August 17, 2019
PubMed
Summary

Salmonella Typhi produces two forms of typhoid toxin with distinct delivery components but shared active subunits. This toxin evolution offers functional versatility, revealing a new paradigm in bacterial toxin biology.

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