Related Experiment Video
Updated: Aug 13, 2026

Measuring the 50% Haemolytic Complement (CH50) Activity of Serum
Published on: March 30, 2010
[Levels of complement components in sera and pleural fluid in patients with various types of pleural pathology]
R Cicioğlu1, N Enacar, G Karabiyikoğlu
1Ilk bölümü I. Ulusal Allerjik Hastaliklar Sempozyumunda, Hacettepe, Ankara.
Insights
This study measured complement components C3c and C4 in serum and pleural fluid from 40 patients with pleural pathology. Findings were compared to existing literature for insights into complement
Area of Science:
- Biochemistry
- Immunology
- Pulmonology
Context:
- Pleural pathology involves diverse conditions affecting the pleura.
- Complement components play a role in inflammatory and immune responses.
- Understanding complement levels in pleural fluid may offer diagnostic or prognostic value.
Purpose:
- To determine serum and pleural fluid levels of complement components C3c and C4.
- To analyze these levels in patients with various pleural pathologies.
- To compare findings with existing literature and discuss their implications.
Summary:
- Serum and pleural fluid levels of complement components C3c and C4 were quantified in 40 patients.
- Results were analyzed in the context of different pleural pathologies.
- The study compared these findings with relevant scientific literature.
Impact:
- Provides data on complement component levels in pleural disease.
- May contribute to understanding the role of complement in pleural pathology.
- Offers a basis for further research into diagnostic markers for pleural conditions.
Abstract:
In this study, the serum and pleural fluid levels of complement components (C3c, C4) of 40 patients with different pleural pathology were determined. The result were compared by the literature and discussed with them.
Related Concept Videos
Pleura of the Lungs
Complement System
Pneumonia III: Complications and Assessment
Pleural Disorders: Types and Brief Description
Pleural Effusion I: Introduction
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's criteria,...
Pleural Effusion II: Symptoms and Management
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:

