Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Fatty Acid Metabolism01:28

Overview of Fatty Acid Metabolism

36.7K
Lipids also are sources of energy that power cellular processes. Like carbohydrates, lipids are composed of carbon, hydrogen, and oxygen, but these atoms are arranged differently. Most lipids are nonpolar and hydrophobic. Major types include fats and oils, waxes, phospholipids, and steroids.
Fatty acids are catabolized in a process called beta-oxidation, which takes place in the matrix of the mitochondria and converts their fatty acid chains into two-carbon units of acetyl groups. The acetyl...
36.7K
Obesity01:24

Obesity

1.1K
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
1.1K
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

232
In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
232
Amino acids03:42

Amino acids

104.6K
Amino acids are the monomers that comprise proteins. Each amino acid has the same fundamental structure, which consists of a central carbon atom, or the alpha (α) carbon, bonded to an amino group (NH2), a carboxyl group (COOH), and to a hydrogen atom. Every amino acid also has another atom or group of atoms bonded to the central atom known as the R group. There are 20 common amino acids present in proteins, each with a different R group. Variation in the amino acid sequence is responsible for...
104.6K
Mixtures of Acids03:27

Mixtures of Acids

21.5K
The pH of a solution containing an acid can be determined using its acid dissociation constant and its initial concentration. If a solution contains two different acids, then its pH can be determined using one of several methods depending upon the relative strength of the acids and their dissociation constants.
A Mixture of a Strong Acid and a Weak Acid
In a mixture of a strong acid and a weak acid, the strong acid dissociates completely and becomes a source of almost all the hydronium ions...
21.5K
Polyprotic Acids03:38

Polyprotic Acids

31.8K
Acids are classified by the number of protons per molecule that they can give up in a reaction. Acids such as HCl, HNO3, and HCN that contain one ionizable hydrogen atom in each molecule are called monoprotic acids. Their reactions with water are:
31.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Serum lactate dehydrogenase is associated with the presence and extent of preoperative peritumoral edema in melanoma brain metastases.

Journal of neuro-oncology·2026
Same author

Digital transformation and the future of dermatology lectures in 2026 - results of a student survey in Leipzig.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2026
Same author

[Multiple itchy, erythrosquamous skin lesions].

Dermatologie (Heidelberg, Germany)·2026
Same author

Diagnostic Accuracy of Ex Vivo Confocal Laser Scanning Microscopy for Routine Detection of Cutaneous Squamous Cell Carcinoma and Actinic Keratoses.

Cancers·2026
Same author

Disc-Toroid Hybrid Lipid Nanoparticles for Efficient Drug Encapsulation and Subcutaneous Delivery.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

[Generalized pustulosis after leflunomide].

Dermatologie (Heidelberg, Germany)·2026

Related Experiment Video

Updated: Jan 20, 2026

Saturated Fatty Acids Induce Ceramide-associated Macrophage Cell Death
08:26

Saturated Fatty Acids Induce Ceramide-associated Macrophage Cell Death

Published on: October 31, 2017

9.7K

Psoriasis: Obesity and Fatty Acids.

Manfred Kunz1, Jan C Simon1, Anja Saalbach1

  • 1Department of Dermatology, Venereology and Allergology, University of Leipzig, Leipzig, Germany.

Frontiers in Immunology
|August 17, 2019
PubMed
Summary

Obesity is a significant environmental risk factor for psoriasis, impacting its onset and severity. This review explores how obesity exacerbates this chronic inflammatory skin disease.

Area of Science:

  • Dermatology
  • Immunology
  • Metabolic Diseases

Background:

  • Psoriasis is a chronic inflammatory disease affecting multiple organ systems.
  • Its pathogenesis involves genetic and environmental factors, including immune dysregulation and inflammatory pathways like TNF-alpha and IL-23/IL-17.
  • Obesity is an emerging, independent risk factor for psoriasis development and severity.

Purpose of the Study:

  • To review the role of obesity as a significant environmental risk factor in psoriasis.
  • To elucidate the mechanisms by which obesity exacerbates psoriasis.

Main Methods:

  • Literature review focusing on studies investigating the link between obesity and psoriasis.
  • Analysis of immunological and metabolic pathways involved in obesity-mediated psoriasis.
Keywords:
fatty acidsgeneticsmetabolismobesitypsoriasis

More Related Videos

Preparation, Purification, and Use of Fatty Acid-containing Liposomes
10:43

Preparation, Purification, and Use of Fatty Acid-containing Liposomes

Published on: February 9, 2018

82.2K
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.4K

Related Experiment Videos

Last Updated: Jan 20, 2026

Saturated Fatty Acids Induce Ceramide-associated Macrophage Cell Death
08:26

Saturated Fatty Acids Induce Ceramide-associated Macrophage Cell Death

Published on: October 31, 2017

9.7K
Preparation, Purification, and Use of Fatty Acid-containing Liposomes
10:43

Preparation, Purification, and Use of Fatty Acid-containing Liposomes

Published on: February 9, 2018

82.2K
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.4K

Main Results:

  • Obesity independently increases the risk and severity of psoriasis.
  • Mechanisms include inflammatory mediator dysregulation and metabolic alterations.
  • The rising global prevalence of obesity highlights its clinical importance in psoriasis.

Conclusions:

  • Obesity is a critical environmental factor driving psoriasis.
  • Understanding obesity-psoriasis mechanisms is crucial for effective management.
  • Further research into these pathways may reveal novel therapeutic targets.