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Updated: Jan 20, 2026

Determining Glucose Metabolism Kinetics Using 18F-FDG Micro-PET/CT
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The role of 18F-FDG PET/CT in early infectious discitis: a case report after a negative MRI

Jorge Juan Fragío-Gil1, Roxana González-Mazarío1, Marta de la Rubia Navarro1

  • 1Rheumatology Department, La Fe Hospital, Avda de Fernando Abril Martorell, 106, Valencia 46026, Spain.

Radiology Case Reports
|August 17, 2019
PubMed

Insights

Fluorine fluodeoxiglucose positron emission tomography/computed tomography (18F-FDG PET/CT) effectively detected infectious discitis missed by MRI. This imaging modality also identified concurrent endocarditis and colonic neoplasm in a patient with Streptococcus gallus bacteria.

Area of Science:

  • Nuclear Medicine
  • Infectious Diseases
  • Oncology

Background:

  • Infectious discitis diagnosis can be challenging, especially with inconclusive Magnetic Resonance Imaging (MRI).
  • Streptococcus gallus (formerly Streptococcus bovis) is associated with serious infections and underlying gastrointestinal pathology.
  • Early detection of infectious discitis and associated conditions is crucial for effective patient management.

Observation:

  • A 70-year-old woman presented with symptoms suggestive of infectious discitis.
  • Initial MRI results for discitis were negative or inconclusive.
  • 18F-FDG PET/CT revealed active discitis, infectious endocarditis, and a colonic neoplasm.

Findings:

  • 18F-FDG PET/CT successfully identified infectious discitis missed by MRI.
  • Culture confirmed Streptococcus gallus as the causative agent.
  • The imaging also detected infectious endocarditis and a colonic neoplasm, highlighting multifocal disease.

Implications:

  • 18F-FDG PET/CT plays a vital role in diagnosing infectious discitis when MRI is equivocal.
  • This imaging technique aids in identifying associated serious conditions like endocarditis and malignancy.
  • Consideration of 18F-FDG PET/CT can improve diagnostic yield and patient outcomes in complex infectious cases.
Keywords:
18F-FDG PET/TCPyogenic vertebral osteomyelitisSpondylodiscitisStreptococcus bovis

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