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Breaking the Barrier of Cancer through Papaya Extract and their Formulation
Sumana Saha1, Tapan Kumar Giri1
1NSHM Knowledge Campus, Kolkata Group of Institutions, 124 BL Saha Road, Kolkata-700053, West Bengal, India.
Background:
In the last decade, many new avenues of cancer treatment have opened up but the costs of treatment have sky-rocketed too. Hence, screening of indigenously available plant and animal resources for anti-carcinogenic potential is an important branch of anticancer research. The effort has been made through this comprehensive review to highlight the recent developments of anticancer therapies using different parts of papaya plant extract.
Methods:
In search of the naturally existing animals and plants for anticarcinogenic potential, papaya plant has been exploited by the scientist working in this research field. A widespread literature search was performed for writing this review.
Results:
Different constituents of Carica papaya responsible for anticancer activities have been discussed. Papaya extract for the treatment of breast, liver, blood, pancreas, skin, prostate, and colon cancer have also been reported. Finally, the various formulation approach using Carica papaya extract have been highlighted.
Conclusion:
The information provided in this review might be useful for researchers in designing of novel formulation of Carica papaya extract for the treatment of cancer.
Insights
Papaya extract shows potential anticancer properties against various cancers, including breast, liver, and colon. This review highlights its therapeutic applications and formulation strategies for cancer treatment.
Area of Science:
- Phytochemistry
- Oncology
- Pharmacology
Background:
- Rising cancer treatment costs necessitate exploring affordable, natural alternatives.
- Indigenous plant resources are increasingly investigated for anticancer potential.
- Papaya (Carica papaya) is a focus for its reported anti-carcinogenic properties.
Purpose of the Study:
- To review recent advancements in anticancer therapies utilizing papaya plant extract.
- To consolidate information on the anticancer constituents and applications of Carica papaya.
Main Methods:
- Comprehensive literature search on Carica papaya and anticancer activity.
- Analysis of scientific studies detailing papaya's role in cancer research.
Main Results:
- Identified various Carica papaya constituents with anticancer activities.
- Reported efficacy of papaya extract against breast, liver, blood, pancreas, skin, prostate, and colon cancers.
- Highlighted different formulation approaches for Carica papaya extract.
Conclusions:
- Papaya extract demonstrates significant potential for cancer treatment.
- Findings may guide researchers in developing novel Carica papaya-based cancer formulations.
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