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E-ABR in Patients with Cochlear Implant: A Comparison between Patients with Malformed Cochlea and Normal Cochlea

Arianna Di Stadio1, Laura Dipietro2, Antonietta De Lucia3

  • 1Department Of Otolaryngology, University of Perugia, Perugia, Italy.

The Journal of International Advanced Otology
|August 17, 2019
PubMed

Insights

Electrical auditory brainstem response (EABR) effectively assesses auditory nerve integrity after cochlear implant (CI) surgery in pediatric patients with normal or malformed cochleas. EABR is a valuable tool for evaluating surgical outcomes, especially in cases of cochlear malformation.

Area of Science:

  • Neuroscience
  • Audiology
  • Otolaryngology

Background:

  • Cochlear implant (CI) surgery is a common treatment for pediatric hearing loss.
  • Assessing auditory nerve integrity post-CI is crucial for surgical success.
  • Cochlear malformations present unique challenges in auditory pathway evaluation.

Purpose of the Study:

  • To compare electrical auditory brainstem response (EABR) in pediatric CI patients with normal cochleas versus cochlear malformations.
  • To evaluate the sensitivity of EABR in detecting auditory nerve function after CI surgery.
  • To assess the utility of EABR for determining CI surgical outcomes.

Main Methods:

  • A case-control study involving 26 pediatric subjects undergoing CI surgery.
  • Group A (n=20) had normal cochleas; Group B (n=6) had cochlear malformations.
  • EABR was recorded immediately (T0) and 6 months (T1) post-surgery, analyzing Waves III and V amplitude and latency.

Main Results:

  • Auditory brainstem response (ABR) was only recordable in Group A.
  • EABR successfully recorded Waves III and V in all subjects at T0 and T1.
  • No significant changes in EABR amplitude or latency were observed between T0 and T1 within groups.
  • A statistically significant difference in average Wave V amplitude was found between groups at both T0 and T1.

Conclusions:

  • EABR is a sensitive and valid tool for assessing auditory nerve integrity post-CI surgery in both normal and malformed cochleas.
  • EABR can detect auditory nerve function even when standard ABR is absent.
  • Pre- and post-operative EABR testing is recommended to monitor outcomes, particularly in patients with cochlear malformations.
Abstract

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