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Related Concept Videos

Pain01:20

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Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
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In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
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Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram
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Pain Neurology.

Victor C Wang1, William J Mullally2

  • 1Department of Neurology, Department of Anesthesia, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.

The American Journal of Medicine
|August 17, 2019
PubMed
Summary
This summary is machine-generated.

Pain perception is complex, involving sensory and emotional responses influenced by various factors. Persistent pain may require specialist consultation for diagnosis and management.

Keywords:
Chronic painLow back painNeuralgiaNeuropathyPain neurologyRadiculopathy

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Area of Science:

  • Neurology
  • Pain Management
  • Psychosomatic Medicine

Background:

  • Pain is a primary reason for medical visits, posing diagnostic and treatment challenges.
  • Pain perception is a complex interplay of sensory input and emotional response.
  • Factors like experience, culture, and mental health influence pain perception and its impact.

Purpose of the Study:

  • To provide a comprehensive overview of pain as a medical complaint.
  • To highlight the multifaceted nature of pain perception.
  • To guide primary care providers on managing persistent pain.

Main Methods:

  • Literature review of pain mechanisms and influencing factors.
  • Analysis of acute and chronic pain conditions.
  • Discussion of diagnostic and therapeutic approaches.

Main Results:

  • Pain is not solely sensory but involves emotional and cognitive components.
  • Acute pain often relates to tissue damage, but exceptions exist (e.g., headaches).
  • Chronic pain causes are diverse, including injury, disease, and unclear mechanisms like fibromyalgia.

Conclusions:

  • Effective pain management requires understanding its complex nature.
  • Persistent pain warrants consideration for specialist referral.
  • Addressing underlying causes is key to pain resolution or improvement.