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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...
Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...

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Introducing Shear Stress in the Study of Bacterial Adhesion
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Morphea masquerading as cellulitis.

Claire Sethu1, Kai Yuen Wong2, Diana Slade-Sharman3

  • 1Plastic & Reconstructive Surgery, John Radcliffe Hospital, Oxford, UK.

BMJ Case Reports
|August 18, 2019
PubMed
Summary
This summary is machine-generated.

Morphea after breast reconstruction is a rare condition. It can be misdiagnosed as infection or inflammation, highlighting the need for accurate diagnosis.

Keywords:
breast surgerydermatologyplastic and reconstructive surgeryskin

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Area of Science:

  • Dermatology
  • Plastic Surgery
  • Oncology

Background:

  • Breast reconstruction is a common procedure for breast cancer patients.
  • Morphea, a type of localized scleroderma, is characterized by skin hardening.
  • Post-surgical complications can arise, necessitating careful differential diagnosis.

Observation:

  • A rare case of morphea developing after breast reconstruction is presented.
  • The morphea presented with skin changes that mimicked infection or inflammation.
  • This highlights a potential diagnostic challenge in the post-operative period.

Findings:

  • Morphea is an uncommon but possible complication following breast reconstruction.
  • Histopathological examination is crucial for differentiating morphea from other conditions.
  • Early and accurate diagnosis is key to appropriate management.

Implications:

  • Awareness of morphea as a differential diagnosis is important for clinicians.
  • Prompt recognition can prevent unnecessary treatments for misdiagnosed conditions.
  • Further research may elucidate the specific risk factors for morphea post-reconstruction.