Related Experiment Video
Updated: Jan 20, 2026

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
Published on: September 27, 2017
The cost of childhood atopic dermatitis in a multi-ethnic Asian population: a cost-of-illness study
M Olsson1,2, R Bajpai1,3, L W Y Wee4
1Centre for Population Health Sciences (CePHaS), Lee Kong Chian School of Medicine, Nanyang Technological University, Clinical Sciences Building, 11 Mandalay Road, Singapore, 308232, Singapore.
Insights
Childhood atopic dermatitis incurs significant costs, primarily from informal caregiving and out-of-pocket expenses. Disease severity strongly influences the economic burden on families and healthcare systems.
Area of Science:
- Health Economics
- Pediatric Dermatology
- Public Health
Background:
- Childhood atopic dermatitis significantly impacts quality of life and incurs substantial healthcare costs.
- Existing cost estimations for childhood atopic dermatitis are often outdated or limited in scope.
Purpose of the Study:
- To comprehensively estimate the economic burden of childhood atopic dermatitis in Singapore.
- To identify factors associated with the economic impact of childhood atopic dermatitis.
Main Methods:
- A cross-sectional cost-of-illness study was conducted from a societal perspective in Singapore.
- Data on sociodemographics, clinical characteristics, healthcare utilization, and caregiving time were collected from caregivers of children under 16 with atopic dermatitis.
- The study period was from December 2016 to December 2017.
Main Results:
- The average annual cost per child was estimated at USD 7943, with costs varying by severity (mild USD 6651, moderate USD 7935, severe USD 14,335).
- Informal caregiving constituted the largest cost component (46%), followed by out-of-pocket expenses (37%).
- Healthcare utilization accounted for 17% of total costs, with medications being a significant factor (43% of healthcare costs).
Conclusions:
- Childhood atopic dermatitis imposes a substantial economic burden, largely driven by informal caregiving and out-of-pocket expenditures.
- The economic impact of atopic dermatitis is closely linked to disease severity.
- Findings provide crucial data for policymakers to develop targeted support for affected families.
Background:
Childhood atopic dermatitis can often have a negative impact on quality of life for affected children and their caregivers. The condition contributes to increased healthcare costs and can pose heavy economic burdens on healthcare systems and societies.
Objectives:
The objective of this study is to provide a comprehensive estimate of the economic burden of childhood atopic dermatitis in a Singaporean sample and to investigate associated factors.
Methods:
This cross-sectional cost-of-illness study applied a societal perspective. Data was collected between December 2016 and December 2017 in Singapore. Caregivers to children below 16 years of age with a physician-confirmed diagnosis of atopic dermatitis were recruited and sociodemographics, clinical characteristics, health service utilization data and time spent on caregiving were collected from all eligible participants.
Results:
The average annual cost per child with atopic dermatitis was estimated at U.S. dollars (USD) 7943 (mild USD 6651, moderate USD 7935 and severe USD 14 335) in 2017 prices. The major cost was for informal caregiving (46% of the total cost) followed by out-of-pocket expenses (37%). Healthcare utilization contributed to 17% of the total cost of which 43% was for medications.
Conclusions:
Childhood atopic dermatitis imposes substantial costs with a large proportion arising from informal caregiving and out-of-pocket expenses. The costs related to atopic dermatitis are also strongly related to disease severity. This information is important for policy makers and other health planners when considering how to better support affected families. What's already known about the topic? Childhood atopic dermatitis is a costly disease for society. However, comprehensive cost estimations are lacking. Previous cost studies are old, based on small sample sizes or are healthcare-setting specific. What does this study add? This study comprises a health economic evaluation assessing different levels of care and includes various categories of costs. The result showed that informal caregiving was the most prominent cost for children with atopic dermatitis.
Related Concept Videos
Ethnic Identity within a Larger Culture
Classification of Illness
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
Factors Affecting Illness
For instance, risk factors are connected to illness,...
Concepts of Health and Illness
Dimensions of Health and Illness
What is Population Genetics?

