Measles-adherent lymphocyte phenomenon of Levy in multiple sclerosis: normal reactivity of blood lymphocytes

The measles-adherent phenomenon described by Levy in multiple sclerosis was investigated by studying the rosetting effect of blood lymphocytes from multiple sclerosis patients and healthy controls on chronically measles infected heteroploid Hela cells (Lu 106). No significant difference in rosetting was observed, irrespective if a lymphocyte/virus infected Lu cell ratio of 10/1 or 50/1 was used. Therefore, the test is not discriminative for multiple sclerosis.