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Noninvasive Imaging to Assess Atherosclerotic Plaque Composition and Disease Activity: Coronary and Carotid

Marwa Daghem1, Rong Bing1, Zahi A Fayad2

  • 1British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.

JACC. Cardiovascular Imaging
|August 19, 2019
PubMed

Insights

Advanced imaging techniques now allow detailed assessment of atherosclerosis plaque composition and activity. This improves risk stratification for cardiovascular disease beyond traditional stenosis measurements.

Area of Science:

  • Cardiovascular imaging
  • Atherosclerosis research
  • Medical diagnostics

Background:

  • Cardiovascular disease is a major global health concern.
  • Traditional atherosclerosis imaging focuses on stenosis and plaque burden.
  • Advances enable noninvasive interrogation of plaque characteristics.

Purpose of the Study:

  • To review multimodality imaging for atherosclerosis.
  • To focus on carotid and coronary applications.
  • To highlight potential improvements in risk stratification and clinical decision-making.

Main Methods:

  • Review of current literature on advanced imaging techniques.
  • Focus on noninvasive methods for plaque characterization.
  • Analysis of applications in carotid and coronary arteries.

Main Results:

  • Novel imaging modalities can assess plaque composition and activity.
  • Differentiation between stable and unstable atherosclerotic plaques is possible.
  • These techniques complement existing imaging assessments.

Conclusions:

  • Multimodality imaging offers enhanced insights into atherosclerosis.
  • Improved risk stratification for cardiovascular events is achievable.
  • These advanced techniques have the potential to refine clinical decision-making.

Keywords:
atherosclerosisplaque burdenpositron emission tomographyvulnerable plaque

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