Related Experiment Video
Updated: Jan 20, 2026

Using Retinal Imaging to Study Dementia
Published on: November 6, 2017
The Long-Term Risk of Dementia after Transient Global Amnesia: A Population-Based Cohort Study in Taiwan
Sun-Wung Hsieh1,2,3, Chun-Hung Chen1,2,3, Poyin Huang1,2,3
1Department of Neurology, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Background:
Transient global amnesia (TGA) is a clinical syndrome characterized by the sudden onset of larger anterograde and milder retrograde amnesia that lasts up to 24 h.
Objectives:
We aimed to investigate the long-term risk of dementia up to 8 years in subjects with TGA.
Method:
We conducted a control cohort study using the Taiwan National Health Insurance Research database from 2005 to 2012 with an 8-year follow-up period. From all potential participants >18 years of age without dementia history, we identified TGA subjects and non-TGA controls with age, gender and comorbidities matched in a 1:3 ratio. The yearly incidence of dementia was compared in TGA and non-TGA cohorts. The cumulative hazard ratio (HR) of dementia was estimated. The risk factors of dementia after TGA were investigated.
Results:
A total of 181 TGA subjects and 543 non-TGA controls were included in the study. There were 14 dementia cases in the 181 TGA cohorts during the follow-up period with yearly incidence rates of 20.14 per 1,000 person. The adjusted HR for dementia in TGA cohorts was 2.23 (95% CI 1.12-4.44, p = 0.023) compared with non-TGA cohorts after adjusting for age, gender and comorbidities. Age and diabetes were significantly associated with dementia in TGA.
Conclusions:
TGA increased the long-term risk of dementia. Age and diabetes were notable factors associated with dementia after TGA.
More Related Videos
Related Concept Videos
Dementia
The progression of dementia is generally gradual....
Amnesia
The severity and duration of memory loss vary depending on the type and underlying cause. Amnesia is classified into two main types: retrograde and anterograde.
Retrograde amnesia is marked by the loss of memories formed before the onset of the condition. Patients may recall distant past events but often forget those occurring shortly before the incident.
Anterograde...
Dissociative Amnesia
Conservation of Small Populations
Global Climate Change
What is Population Genetics?

