Related Experiment Video

Updated: Jan 20, 2026

Myocardial Infarction and Functional Outcome Assessment in Pigs
12:03

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

28.6K

Major Adverse Cardiovascular Events: An Inevitable Outcome of ST-elevation myocardial infarction? A Literature Review

Ishan Poudel1, Chavi Tejpal2, Hamza Rashid3

  • 1Internal Medicine, Department of Research, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.

Cureus
|August 20, 2019
PubMed

Insights

Major adverse cardiovascular events (MACE) are a significant risk for patients with ST-elevation myocardial infarction (STEMI). This review found MACE incidence in STEMI patients ranges widely from 4.2% to 51%.

Area of Science:

  • Cardiology
  • Clinical Research

Background:

  • ST-elevation myocardial infarction (STEMI) is a critical condition associated with high mortality and morbidity.
  • Major adverse cardiovascular events (MACE) are the primary drivers of poor outcomes in STEMI patients.

Purpose of the Study:

  • To analyze the occurrence and incidence of MACE in patients diagnosed with STEMI.
  • To review existing literature on MACE following STEMI, irrespective of treatment and follow-up duration.

Main Methods:

  • A comprehensive PubMed search was conducted for studies on STEMI, yielding 24,244 articles.
  • Inclusion/exclusion criteria were applied, resulting in 75 relevant articles for analysis.
  • The reviewed studies included cohort studies, clinical trials (RCTs), case-control, cross-sectional, review articles, and observational studies.

Main Results:

  • MACE remains a significant adverse outcome for STEMI patients.
  • The incidence of MACE in STEMI patients varied widely, ranging from 4.2% to 51%.
  • This incidence was observed irrespective of the treatment modality and across follow-up periods up to 10 years post-diagnosis.

Conclusions:

  • MACE represents a substantial risk in the STEMI population.
  • The wide incidence range highlights variability in patient populations, follow-up durations, and outcome definitions across studies.
  • Further research may be needed to standardize reporting and understand factors influencing MACE occurrence in STEMI.

Keywords:
stemistemi complicationsstemi major adverse cardiovascular eventsstemi review

More Related Videos

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction14:19

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

Published on: October 14, 2016

12.0K
Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction05:26

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction

Published on: May 28, 2019

9.6K

Related Concept Videos

Freezing Point Depression and Boiling Point Elevation03:12

Freezing Point Depression and Boiling Point Elevation

Boiling Point Elevation
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
39.6K
Review and Preview01:10

Review and Preview

In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
8.3K
Review and Preview01:13

Review and Preview

Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
10.9K
Outcomes of Glycolysis01:13

Outcomes of Glycolysis

Nearly all the energy used by cells comes from the bonds that make up complex organic compounds. These organic compounds are broken down into simpler molecules, such as glucose. As a result, cells extract energy from glucose over many chemical reactions—a process called cellular respiration.
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
106.8K
Major Organs of the Digestive System01:19

Major Organs of the Digestive System

The digestive system is responsible for the ingestion of food, secretion of enzymes, mixing and digesting food, absorption of the nutrients and defecation. The human digestive system consists of two major parts: the gastrointestinal tract and the accessory digestive organs.
Gastrointestinal tract:
8.8K
Major Losses in Pipes01:28

Major Losses in Pipes

When a fluid flows through a pipe, it experiences energy losses due to frictional resistance along the pipe walls, known as major losses. These energy losses result in a pressure drop, which varies based on the flow conditions — whether laminar or turbulent — and the specific physical properties of the fluid and pipe.
Fluid flow can be classified as laminar or turbulent, primarily based on the Reynolds number. This dimensionless number reflects the relative influence of inertial to viscous...
1.9K