Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

975
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
975
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

916
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
916
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

459
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
459
Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

538
Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
538
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

646
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
646
Alterations in Respiration II01:30

Alterations in Respiration II

1.7K
There are numerous types of normal and abnormal respiration. Based on ventilatory movements, breathing patterns are classified as regular, deep, or shallow. Examples include Biot's breathing, Cheyne-Stokes respiration, Kussmaul's breathing, hyperventilation, and hypoventilation. Each pattern is clinically significant and aids in evaluating patients.
In Biot's breathing, the respiratory rate and depth are irregular, alternating between periods of deep gasping and apnea. Common causes...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Glucagon-stimulated copeptin response in children: a proof-of-concept study.

Frontiers in endocrinology·2026
Same author

Multimodal engagement estimation in paediatric robot-assisted gait training: integrating physiological sensing and biomechanical interaction.

Journal of neuroengineering and rehabilitation·2026
Same author

Driving Change in Rehabilitation Practice: Expert Insights and Strategic Direction for Integrating ISPRM's Clinical Functioning Information Tool (ClinFIT) in Clinical Practice and Research.

American journal of physical medicine & rehabilitation·2026
Same author

Creating a ClinFIT, the International Society of Physical and Rehabilitation Medicine's Clinical Functioning Information Tool, that Works for you.

American journal of physical medicine & rehabilitation·2026
Same author

Knowledge and use of the international classification of functioning, disability and health: a cross-sectional survey among health professionals in Pakistan.

Frontiers in rehabilitation sciences·2026
Same author

SIMFER guidelines on physical modalities for chronic primary pain management.

European journal of physical and rehabilitation medicine·2026

Related Experiment Video

Updated: Jan 20, 2026

Dynamic Adhesion Assay for the Functional Analysis of Anti-adhesion Therapies in Inflammatory Bowel Disease
08:27

Dynamic Adhesion Assay for the Functional Analysis of Anti-adhesion Therapies in Inflammatory Bowel Disease

Published on: September 20, 2018

8.1K

Bone alterations in inflammatory bowel diseases.

Dolores Sgambato1, Francesca Gimigliano2, Cristiana De Musis1

  • 1Departments of Precision Medicine and Polyspecialistic Internal Medicine, University of Campania ''Luigi Vanvitelli'' and University Hospital, Naples 80131, Italy.

World Journal of Clinical Cases
|August 20, 2019
PubMed
Summary
This summary is machine-generated.

Inflammatory bowel diseases (IBD) can lead to metabolic bone disease (MBD), causing bone density loss like osteopenia and osteoporosis. Early screening and treatment are crucial for managing bone fragility in IBD patients.

Keywords:
Bone alterationsBone mineral densityCrohn’s diseaseInflammatory bowel diseasesOsteopeniaOsteoporosisUlcerative colitis

More Related Videos

DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat
09:04

DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat

Published on: February 27, 2014

48.6K
Effects of Taste Signaling Protein Abolishment on Gut Inflammation in an Inflammatory Bowel Disease Mouse Model
09:31

Effects of Taste Signaling Protein Abolishment on Gut Inflammation in an Inflammatory Bowel Disease Mouse Model

Published on: November 9, 2018

9.1K

Related Experiment Videos

Last Updated: Jan 20, 2026

Dynamic Adhesion Assay for the Functional Analysis of Anti-adhesion Therapies in Inflammatory Bowel Disease
08:27

Dynamic Adhesion Assay for the Functional Analysis of Anti-adhesion Therapies in Inflammatory Bowel Disease

Published on: September 20, 2018

8.1K
DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat
09:04

DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat

Published on: February 27, 2014

48.6K
Effects of Taste Signaling Protein Abolishment on Gut Inflammation in an Inflammatory Bowel Disease Mouse Model
09:31

Effects of Taste Signaling Protein Abolishment on Gut Inflammation in an Inflammatory Bowel Disease Mouse Model

Published on: November 9, 2018

9.1K

Area of Science:

  • Gastroenterology and Endocrinology
  • Bone Metabolism Research

Background:

  • Inflammatory bowel diseases (IBD) encompass Crohn's disease and ulcerative colitis, often presenting with multifactorial etiologies.
  • Extraintestinal manifestations are common in IBD, affecting up to 50% of patients.
  • Metabolic bone disease (MBD), including osteopenia and osteoporosis, is a significant extraintestinal manifestation in IBD.

Purpose of the Study:

  • To review the prevalence and pathophysiology of metabolic bone alterations in IBD.
  • To identify key risk factors contributing to bone fragility in IBD patients.
  • To emphasize the importance of screening, prophylaxis, and treatment of MBD in IBD.

Main Methods:

  • Literature review focusing on IBD and metabolic bone disease.
  • Analysis of factors contributing to bone density reduction in IBD.
  • Synthesis of current understanding on risk factors, screening, and management.

Main Results:

  • Bone alterations in IBD are multifactorial, influenced by inflammation, genetics, lifestyle, and treatment side effects.
  • Key contributing factors include decreased physical activity, inflammation-induced bone resorption, malabsorption, vitamin D deficiency, and steroid use.
  • Gut-bone immune signaling and microbiota interactions also play a role in bone density changes.

Conclusions:

  • Metabolic bone disease is a prevalent complication of IBD with significant impact on patient health.
  • Comprehensive management strategies including screening and targeted therapies are essential for IBD patients.
  • Addressing MBD is critical for improving the overall well-being and reducing fracture risk in individuals with IBD.