Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Structural Protein Function01:56

Structural Protein Function

29.8K
Structural proteins are a category of proteins responsible for functions ranging from cell shape and movement to providing support to major structures such as bones, cartilage, hair, and muscles. This group includes proteins such as collagen, actin, myosin, and keratin.
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity.  In bones and teeth, it mineralizes to...
29.8K
Structural Protein Function01:56

Structural Protein Function

3.2K
3.2K
Mechanical Protein Functions01:58

Mechanical Protein Functions

5.5K
Proteins perform many mechanical functions in a cell. These proteins can be classified into two general categories- proteins that generate mechanical forces and proteins that are subjected to mechanical forces. Proteins providing mechanical support to the structure of the cell, such as keratin, are subjected to mechanical force, whereas proteins involved in cell movement and transport of molecules across cell membranes, such as an ion pump, are examples of generating mechanical force. 
5.5K
Theory of Attribution I: Correspondent Inference Theory01:15

Theory of Attribution I: Correspondent Inference Theory

460
Correspondent inference theory, proposed by Jones and Davis in 1965, seeks to explain how individuals infer stable personality traits from observed behaviors. It suggests that people attribute actions to underlying dispositions rather than external circumstances, particularly when the behavior appears intentional and socially significant.Voluntary Behavior and Dispositional AttributionAccording to this theory, individuals are more likely to attribute behavior to personal traits when it appears...
460
Mechanical Protein Function01:58

Mechanical Protein Function

2.5K
2.5K
Cis-regulatory Sequences02:02

Cis-regulatory Sequences

11.6K
Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...
11.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Predictors of Hypertensive Disorders of Pregnancy in Japan: A Population-Based Retrospective Cohort Study Using the Shizuoka Kokuho Database.

The journal of obstetrics and gynaecology research·2026
Same author

Isolated Low Levels of High-density Lipoprotein Cholesterol are Associated with an Increased Risk of Ischemic Cardiovascular Events: The Shizuoka Kokuho Database Study.

Journal of atherosclerosis and thrombosis·2026
Same author

Is BMI a Mediator in the Association Between Subjective Masticatory Function and Functional Disability? Findings From the Shizuoka Kokuho Database Study.

Gerodontology·2026
Same author

Systemic and local predictors of medication-related osteonecrosis of the jaw in patients receiving antiresorptive therapy: The Shizuoka Kokuho Database study.

Bone·2026
Same author

Measurement of Atrial Natriuretic Peptide (ANP) Concentrations in Human Breast Milk and Maternal Plasma During Carperitide Therapy (Two Case Reports).

Journal of human lactation : official journal of International Lactation Consultant Association·2026
Same author

KEGG Syntax for comparison of organisms, organism groups, and viruses by conserved gene repertoires.

Protein science : a publication of the Protein Society·2026

Related Experiment Video

Updated: Jan 20, 2026

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3
11:10

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3

Published on: December 27, 2010

12.7K

KEGG Mapper for inferring cellular functions from protein sequences.

Minoru Kanehisa1, Yoko Sato2

  • 1Institute for Chemical Research, Kyoto University, Uji, Kyoto, Japan.

Protein Science : a Publication of the Protein Society
|August 20, 2019
PubMed
Summary

KEGG Mapper provides updated tools for interpreting large biological datasets by mapping genes to molecular networks. This facilitates understanding cellular functions and organism-level features using KEGG Orthology identifiers.

Keywords:
KEGGKEGG MapperKEGG OrthologyKEGG modulegenome annotationpathway analysis

More Related Videos

A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing
11:36

A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing

Published on: July 3, 2016

11.3K
Identification of Functional Protein Regions Through Chimeric Protein Construction
11:39

Identification of Functional Protein Regions Through Chimeric Protein Construction

Published on: January 8, 2019

10.9K

Related Experiment Videos

Last Updated: Jan 20, 2026

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3
11:10

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3

Published on: December 27, 2010

12.7K
A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing
11:36

A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing

Published on: July 3, 2016

11.3K
Identification of Functional Protein Regions Through Chimeric Protein Construction
11:39

Identification of Functional Protein Regions Through Chimeric Protein Construction

Published on: January 8, 2019

10.9K

Area of Science:

  • Bioinformatics
  • Systems Biology
  • Genomics

Background:

  • KEGG (Kyoto Encyclopedia of Genes and Genomes) is a vital resource for interpreting large-scale molecular data.
  • It integrates experimental knowledge into molecular networks, including pathways, hierarchies, and modules.
  • KEGG mapping translates genomic data into these networks for functional interpretation.

Purpose of the Study:

  • To introduce a new version of KEGG Mapper, a suite of tools for KEGG mapping.
  • To present KOALA family tools for automatic assignment of KEGG Orthology (KO) identifiers.

Main Methods:

  • KEGG mapping utilizes gene sets to generate KEGG molecular networks.
  • KOALA tools automate the assignment of KEGG Orthology identifiers.
  • The updated KEGG Mapper is accessible via the KEGG website.

Main Results:

  • A new version of KEGG Mapper is now available.
  • Enhanced tools facilitate the interpretation of large-scale molecular datasets.
  • Automatic KO assignment is streamlined with KOALA tools.

Conclusions:

  • The updated KEGG Mapper and KOALA tools improve the biological interpretation of genomic and metagenomic data.
  • These resources enhance the understanding of cellular and organism-level functions.
  • KEGG continues to be a cornerstone for biological data analysis.