Outer Retinal Healing After Internal Limiting Membrane Peeling in Diabetic Macular Oedema with Vitreomacular
1Department of ophthalmology, Kasr Alainy medical school, Cairo University, Giza, Egypt.
Abstract:
Purpose: To evaluate the difference in ellipsoid zone and external limiting membrane (EZ/ELM) restoration after vitrectomy with internal limiting membrane (ILM) peeling in diabetic macular oedema with vitreomacular interface abnormalities (VMA DME) patients using 3 different dyes.Methods: Patients with type 2 diabetes mellitus and VMA DME indicated for ILM peelings were included. Disruption of the EZ/ELM was graded and compared among groups (preoperative and 6 months postoperative). Patients were divided into 3 groups according to the dye used: group A: indocyanine green (ICG); group B: trypan blue (TB); and group C: brilliant blue G(BBG).Results: Twenty-six eyes were included in group A, 29 eyes were included in group B, and 28 eyes were included in group C. Improvement in EZ/ELM integrity was observed in 34.6% of group A, 27.6% of group B, and 32.1 % of group C (p = .84). Deterioration of EZ/ELM integrity was observed in 19.2% of group A, 6.9% of group B and 0% of group C (p = .03).Conclusion: ICG resulted in a greater percentage of deteriorated EZ/ELM integrity at 6 months after surgery in cases with pre-treatment ELM interruption. Therefore, ICG should be used with caution in cases with ELM disruption, yet, further studies are recommended.
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