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[Pulse wave velocity and ambulatory blood pressure in essential arterial hypertension]
Insights
Arterial stiffness, measured by pulse wave velocity (PWV), correlates better with blood pressure (BP) measured by ambulatory monitoring than with traditional methods in hypertensive patients. This suggests ambulatory BP monitoring is superior for assessing cardiovascular risk.
Area of Science:
- Cardiology
- Vascular Physiology
- Hypertension Research
Background:
- Cardiovascular complications in hypertensive patients often stem from large artery damage.
- Arterial distensibility is a key indicator of vascular health.
- Assessing blood pressure accurately is crucial for managing hypertension.
Purpose of the Study:
- To evaluate arterial distensibility using carotid-femoral pulse wave velocity (PWV) in patients with sustained essential hypertension.
- To compare the correlation between PWV and blood pressure (BP) measurements obtained from three different methods.
- To determine which BP measurement method best reflects target organ damage in hypertension.
Main Methods:
- Carotid-femoral pulse wave velocity (PWV) was measured in 22 patients with sustained essential hypertension.
- Blood pressure (BP) was measured using a mercury sphygmomanometer, a semi-automatic Dinamap device, and 24-hour ambulatory BP monitoring (Spacelabs Monitor).
- Correlation coefficients were calculated between PWV and BP values from each measurement method.
Main Results:
- PWV showed no correlation with BP measured by mercury sphygmomanometer.
- PWV demonstrated a strong positive correlation with BP measured by the Dinamap device and ambulatory monitoring.
- The strongest correlation was observed between PWV and daytime systolic BP measured by ambulatory monitoring.
Conclusions:
- Ambulatory blood pressure monitoring correlates more strongly with arterial distensibility (PWV) than traditional BP measurement methods.
- Ambulatory BP monitoring may provide a more accurate assessment of cardiovascular risk and target organ damage in hypertensive patients.
- These findings highlight the clinical utility of ambulatory BP monitoring in managing hypertension and preventing cardiovascular events.
Abstract:
Cardiovascular morbidity and mortality of hypertensive patients is mainly related to lesions of large arteries. Arterial distensibility estimated by carotid-femoral pulse wave velocity (PWV) was evaluated in 22 patients with sustained essential hypertension, together with three different methods of blood pressure (BP) measurement: mercury sphygmomanometer, semi-automatic BP recording using the Dinamap apparatus and 24 H ambulatory BP monitoring using the Spacelabs Monitor (5200). Table shows that, while PWV was not correlated with BP measured by mercury sphygmomanometer, it was strongly and positively correlated with BP measured by the other procedures. The best correlation coefficient was noted for the systolic BP measured in the Day Time (7 h-22 h) by the ambulatory method. This study shows that BP Monitoring correlates more strongly than clinic or casual BP with indices of target organ damage. (Table: see text).