Related Experiment Videos
[Reproducibility and development of pulse wave velocity at rest and during exertion]
J P Siché1, R de Gaudemaris, J M Mallion
1Centre de consultation d'hypertension artérielle, médecine interne et cardiologie, hôpital A.-Michallon, CHRU, Grenoble.
Purpose:
to search in which situation the PWV is the most reproducible.
Methodology:
PWV is measured with a continuous doppler technique along the subclavial radial arterial segment on the right forearm. 30 normotensive subjects (20-30 years) are studied twice running at 24-hour interval at rest and during stress (ergometric bicycle, stress levels: 50, 75, 100 watts/mn).
Statistics:
Student test and correlation when the data are normally distributed.
Results:
mean PWV increases progressively with blood pressure during stress. REST: 10.0, 50W: 11.3, 75W: 12.33, 100W: 13.32, 4 mn rest: 10.6. Mean differences (MD) with standard deviations (SD) and correlation (COR) are as following: (Table: see text). If we take into consideration MD, SD and COR between the 2 stress tests, 75W level appears to be the most reproducible.
Conclusion:
these data must be taken into account when using PWV to appreciate the vascular effect of some medications especially in hypertension.