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B Jelle Visser1,2, Marieke Bierhoff1, Tom van Gool3

  • 1Amsterdam UMC, afd. Infectieziekten, Amsterdam.

Nederlands Tijdschrift Voor Geneeskunde
|August 20, 2019
PubMed
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Imported malaria affects 200-300 people annually in the Netherlands. Treatment varies by severity, with artemisinin-based combination therapy (ACT) as a primary option, and chloroquine for specific Plasmodium species.

Area of Science:

  • Tropical medicine
  • Infectious diseases
  • Public health

Background:

  • Imported malaria is diagnosed in 200-300 individuals yearly in the Netherlands.
  • Malaria presents with non-specific symptoms, complicating early diagnosis.
  • Current diagnostic standards rely on blood smear microscopy, with newer methods emerging.

Purpose of the Study:

  • To outline current diagnostic and treatment strategies for malaria in the Netherlands.
  • To detail malaria management protocols for uncomplicated, severe, and pregnancy-related cases.

Main Methods:

  • Review of current clinical guidelines and treatment protocols for malaria.
  • Description of diagnostic techniques, including microscopy and emerging methods.
  • Summary of therapeutic options based on malaria severity and Plasmodium species.

Related Experiment Videos

Main Results:

  • Artemisinin-based combination therapy (ACT) is the standard for uncomplicated malaria.
  • Chloroquine serves as an alternative for specific Plasmodium species (P. vivax, P. knowlesi, P. ovale, P. malariae).
  • Intravenous artesunate followed by oral ACT is the protocol for severe malaria and malaria in pregnancy.

Conclusions:

  • Malaria diagnosis in the Netherlands relies on blood smears, with evolving techniques.
  • Treatment regimens are tailored to disease severity and Plasmodium species.
  • No malaria vaccine is currently available for travelers, emphasizing prevention and prompt treatment.