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Structure of the Centromere Binding Factor 3 Complex from Kluyveromyces lactis

Phong D Lee1, Hui Wei2, Dongyan Tan3

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, 02115, USA; Graduate Program in Virology, Harvard Medical School, Boston, MA, 02115, USA.

Journal of Molecular Biology
|August 20, 2019
PubMed
Summary

Kinetochore protein complexes in budding yeast were structurally analyzed. Differences in the CBF3 complex between Kluyveromyces lactis and Saccharomyces cerevisiae were identified, explaining variations in centromere DNA.

Keywords:
budding yeastcentromeric nucleosome assemblyelectron cryomicroscopykinetochorepoint centromere

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