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The titration of a weak acid with a strong base results in the formation of water and the conjugate base of the acid. For instance, titrating acetic acid with sodium hydroxide leads to the formation of water and sodium acetate. A solution of acetic acid and sodium acetate constitutes a buffer whose relative concentration at different stages of the titration is indicated by the α values, which represent percentages of the weak acid and its conjugate base.
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Matter: Pure Substances and Mixtures
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Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold
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Magnesium-Based Bioactive Composites Processed at Room Temperature.

Moara M Castro1, Debora R Lopes2, Renata B Soares2

  • 1Department of Metallurgical and Materials Engineering, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.

Materials (Basel, Switzerland)
|August 21, 2019
PubMed
Summary
This summary is machine-generated.

Magnesium composites with hydroxyapatite and bioactive glass were created using high-pressure torsion. The magnesium-hydroxyapatite composite showed promising mechanical strength and corrosion resistance for biomedical applications.

Keywords:
bioactive glassbiodegradable materialcompositeshigh-pressure torsionhydroxyapatitemagnesium

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Area of Science:

  • Biomaterials Science
  • Materials Engineering
  • Metallurgy

Background:

  • Magnesium alloys are promising for biodegradable implants due to their mechanical properties and biocompatibility.
  • Developing magnesium composites with enhanced bioactivity and controlled degradation is crucial for orthopedic applications.

Purpose of the Study:

  • To investigate the consolidation and properties of magnesium and AZ91 magnesium alloy composites incorporating hydroxyapatite and bioactive glass particles.
  • To evaluate the mechanical strength, cell viability, and corrosion behavior of these novel magnesium-based biomaterials.

Main Methods:

  • Pure magnesium and AZ91 alloy were reinforced with hydroxyapatite and bioactive glass particles.
  • High-pressure torsion (HPT) was employed for room-temperature consolidation of the composite powders.
  • Mechanical testing, cell viability assays, and immersion tests in Hank's solution were conducted.

Main Results:

  • Bioactive particles were well-dispersed in the metal matrix after HPT processing.
  • Full consolidation was achieved for pure magnesium composites, while AZ91 composites showed incomplete consolidation.
  • The magnesium-hydroxyapatite composite exhibited tensile strength over 150 MPa, good cell viability, and reduced corrosion rates.
  • Composites with bioactive glass showed rapid corrosion and calcium phosphate formation after immersion.

Conclusions:

  • High-pressure torsion is effective for consolidating magnesium-bioactive particle composites, particularly with pure magnesium.
  • The magnesium-hydroxyapatite composite demonstrates potential as a biodegradable implant material due to its mechanical properties and corrosion resistance.
  • Further optimization is needed for AZ91-based composites and those with bioactive glass to control degradation for specific biomedical applications.