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Updated: Jan 20, 2026
10:46
MRI and PET in Mouse Models of Myocardial Infarction
Published on: December 19, 2013
12.3K
PET and MRI based RT treatment planning: Handling uncertainties
1Institut Jules Bordet, Brussels, Belgium.
Summary
Advanced imaging, including PET and MRI, is crucial for radiotherapy. Understanding imaging uncertainties and ensuring quality assurance through collaboration improves treatment accuracy and patient outcomes.
Area of Science:
- Radiotherapy and Medical Imaging
Background:
- Multi-modality imaging is fundamental in radiotherapy for target delineation, treatment guidance, and outcome assessment.
- Functional imaging is increasingly integrated alongside anatomical imaging for enhanced radiotherapy applications.
Purpose of the Study:
- To provide an overview of imaging techniques in radiotherapy, emphasizing uncertainties and quality assurance (QA).
- To highlight the importance of collaboration between radiology, nuclear medicine, and radiotherapy departments.
Main Methods:
- Focus on Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI), with a discussion on Dynamic Contrast-Enhanced Computed Tomography (DCE-CT).
- Emphasis on developing joint imaging protocols and QA programs.
- Addressing uncertainties in image registration and their integration into Planning Target Volume (PTV) margins.
Main Results:
- Proper windowing for PET and understanding MRI sequences are critical for accurate image interpretation.
- Systematic radiologist involvement and multidisciplinary meetings are essential when geometrical distortions are present.
- Functional imaging for dose painting and response assessment requires strong interdepartmental collaboration.
Conclusions:
- Close collaboration between departments is key to improving radiotherapy quality.
- Accurate determination and integration of imaging uncertainties into PTV margins are mandatory.
- Awareness of the limitations of imaging-based biomarkers is crucial for reliable outcome prediction.
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