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Updated: Jan 20, 2026

Cross-Modal Multivariate Pattern Analysis
Published on: November 9, 2011
Prevalence and patterns of multimorbidity among the elderly in China: a cross-sectional study using national survey
Ran Zhang1, Yun Lu1, Liuyan Shi1
1School of International Pharmaceutical Business, China Pharmaceutical University, Nanjing, China.
Objectives:
Examination of the prevalence and patterns of multimorbidity among the elderly in China.
Design:
Cross-sectional study.
Setting:
More than 10 000 households in 28 of the 34 provinces of mainland China.
Participants:
11 707 Chinese adults aged 60 and over.
Primary Outcome Measures:
Prevalence and patterns of multimorbidity among the participants. Relative risks were calculated to estimate the probability of up to 14 chronic conditions coexisting with each other. Observed-to-expected (O/E) ratios were used to analyse the patterns of multimorbidity.
Results:
Multimorbidity was present in 43.6% of respondents from the sample population, with women having the greater prevalence compared with men. There were 804 different comorbidity combinations identified, including 76 dyad combinations and 169 triad combinations. The top 10 morbidity dyads and triads accounted for 69.01% and 47.05% of the total dyad and triad combinations observed, respectively. Among the 14 chronic conditions included in the study, asthma, stroke, heart attack and six other chronic conditions were the main components of multimorbidity due to their high relative risk ratios. The most frequently occurring clusters with higher O/E ratios were stroke along with emotional, nervous, or psychiatric problems; memory-related diseases together emotional, nervous, or psychiatric problems; and memory-related diseases and asthma accompanied by chronic lung diseases and asthma.
Conclusions:
The results of this study highlight the high prevalence of multimorbidity in the elderly population in China. Further studies are required to understand the aetiology of multimorbidity, and future primary healthcare policies should be made while taking multimorbidity into consideration.
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