Related Experiment Video

Updated: Jan 20, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

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MT-DRAGON score for outcome prediction in acute ischemic stroke treated by mechanical thrombectomy within 8 hours

Wagih Ben Hassen1, Nicolas Raynaud2, Nicolas Bricout3

  • 1Neuroradiology, Centre Hospitalier Sainte Anne, Paris, France.

Journal of Neurointerventional Surgery
|August 21, 2019
PubMed
Abstract

Insights

The MT-DRAGON score reliably predicts 3-month outcomes in acute ischemic stroke patients undergoing mechanical thrombectomy. This simple score combines clinical and imaging data for accurate prognosis.

Area of Science:

  • Neurology
  • Radiology
  • Stroke Medicine

Background:

  • The MRI-DRAGON score predicts outcomes in acute ischemic stroke (AIS) patients treated with IV tPA.
  • Mechanical thrombectomy (MT) is a key treatment for AIS, necessitating outcome prediction tools.

Purpose of the Study:

  • To adapt and validate the MRI-DRAGON score for predicting 3-month outcomes in AIS patients treated with MT.
  • To develop the MT-DRAGON score using a large, multicenter cohort.

Main Methods:

  • Retrospective review of 1077 AIS patients treated with MT (Jan 2015-Dec 2017).
  • Derived the MT-DRAGON score by adapting MRI-DRAGON variables (age, NIHSS, glucose, pre-mRS, DWI-ASPECTS) and including time to groin puncture and occlusion site.
  • Defined unfavorable outcome as modified Rankin Scale (mRS) score >2 at 3 months. Evaluated performance using c-statistics and external validation.

Main Results:

  • Included 679 patients (431 derivation, 248 validation). Unfavorable outcome rates were 51.5% (derivation) and 58.1% (validation).
  • The MT-DRAGON score demonstrated strong predictive performance: c-statistics of 0.83 (derivation) and 0.80 (validation).
  • High MT-DRAGON scores (≥11) predicted unfavorable outcomes (n=55), while low scores (≤2) predicted favorable outcomes (95% of 63 patients).

Conclusions:

  • The MT-DRAGON score is a validated, simple tool for predicting 3-month outcomes in patients undergoing MT for AIS.
  • The score effectively integrates clinical and radiological parameters for reliable prognostic assessment.
Keywords:
strokethrombectomy

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