Related Experiment Video

Updated: Jan 20, 2026

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment
08:36

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment

Published on: April 19, 2024

1.1K

Statin treatment after acute coronary syndrome: Adherence and reasons for non-adherence in a randomized controlled

Huber Daniel1, Wikén Christian2, Henriksson Robin2

  • 1Department of Public Health and Clinical Medicine, Unit of Research, Education and Development - Östersund, Umeå University, Östersund, Sweden. daniel.huber@regionjh.se.

Scientific Reports
|August 21, 2019
PubMed

Insights

Nurse-led telemedical follow-up improved statin adherence in acute coronary syndrome (ACS) patients. This secondary prevention strategy led to greater use of potent statins and lower LDL cholesterol compared to usual care.

Area of Science:

  • Cardiology
  • Preventive Medicine
  • Nursing Research

Background:

  • Secondary prevention of cardiovascular disease often shows suboptimal adherence to guideline targets.
  • Acute coronary syndrome (ACS) survivors require effective long-term management to reduce recurrent events.

Purpose of the Study:

  • To evaluate the impact of a nurse-led telemedical follow-up program on statin adherence in ACS patients.
  • To identify reasons for statin discontinuation and compare outcomes between intervention and usual care groups.

Main Methods:

  • Randomized controlled trial (NAILED-ACS) involving ACS patients from 2010-2014.
  • Intervention group received nurse-led annual follow-up with telephone-guided medical titration.
  • Usual care group received standard follow-up; statin discontinuations were tracked for 36 months.

Main Results:

  • The nurse-led intervention increased long-term statin adherence and the proportion of patients on potent statin therapy.
  • Intervention group showed a higher initial risk of statin discontinuation but a lower risk of permanent discontinuation.
  • Female gender was identified as a predictor for statin discontinuation.

Conclusions:

  • A nurse-led telemedical secondary prevention program enhances statin adherence and improves lipid profiles in ACS patients compared to usual care.
  • Structured, longer-term follow-up is crucial to mitigate initial tendencies toward early statin discontinuation in the intervention group.

More Related Videos

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain03:26

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain

Published on: March 8, 2024

3.5K
In situ Subcellular Fractionation of Adherent and Non-adherent Mammalian Cells09:20

In situ Subcellular Fractionation of Adherent and Non-adherent Mammalian Cells

Published on: July 23, 2010

16.3K

Related Concept Videos

Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
855
Acute Coronary Syndrome V: Nursing Management01:26

Acute Coronary Syndrome V: Nursing Management

Nursing Assessment:Nursing management of acute coronary syndrome (ACS) involves taking the patient's history, focusing on primary complaints such as chest pain, dyspnea, and excessive sweating (diaphoresis), as well as other symptoms like back or jaw pain, nausea, vomiting, palpitations, dizziness, and fatigue. The nurse also reviews the patient's history of cardiac events, risk factors such as hypertension, diabetes, smoking, family history, and current medications.In the objective assessment,...
280
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
369
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
222
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
229
Reason and Intuition01:37

Reason and Intuition

The human brain processes information for decision-making using one of two routes: an intuitive system and a rational system (Epstein, 1994; popularized by Kahneman, 2011 as System 1 and System 2, respectively). The intuitive system is quick, impulsive, and operates with minimal effort, relying on emotions or habits to provide cues for what to do next, while the rational system is logical, analytical, deliberate, and methodical. Research in neuropsychology suggests that the...
7.4K