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Related Concept Videos

Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

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The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
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Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
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Updated: Jan 20, 2026

Robotic Lateral Pancreaticojejunostomy for Chronic Pancreatitis
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Advanced imaging techniques for chronic pancreatitis.

Anushri Parakh1, Temel Tirkes2

  • 1Radiology, Massachusetts General Hospital, White 270 | 55 Fruit Street, Boston, 02114, USA.

Abdominal Radiology (New York)
|August 21, 2019
PubMed
Summary
This summary is machine-generated.

Magnetic resonance imaging (MRI) and magnetic resonance cholangiopancreatography (MRCP) are vital for diagnosing chronic pancreatitis (CP). Advanced MRI techniques offer quantitative metrics for assessing acinar cell loss and improving CP diagnosis.

Keywords:
Chronic pancreatitisComputerized tomographyDiffusion-weighted imagingExtracellular volumeMRCPMRIQuantitative imagingT1 mappingVirtual unenhanced images

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Area of Science:

  • Radiology and Medical Imaging
  • Gastroenterology
  • Pancreatic Diseases

Background:

  • Chronic pancreatitis (CP) diagnosis relies on imaging the pancreas and its ducts.
  • MRI/MRCP shows higher sensitivity than CT for mild to moderate CP, detecting ductal and gland changes.
  • Conventional imaging has limitations, with MRI/MRCP missing calcifications and CT providing limited functional information.

Purpose of the Study:

  • To review advanced imaging techniques for chronic pancreatitis diagnosis.
  • To explore the benefits of quantitative MRI and emerging AI applications in CT.
  • To highlight the need for combined ductal and parenchymal imaging criteria for CP.

Main Methods:

  • Review of advanced imaging modalities including MRI, MRCP, CT, and ultrasound.
  • Discussion of quantitative MR imaging for assessing acinar cell loss.
  • Exploration of radiomics and AI applications in multi-detector CT (MDCT).

Main Results:

  • MRI/MRCP is sensitive for early CP changes but does not detect calcifications.
  • Quantitative MRI offers potential for objective assessment of acinar cell loss.
  • MDCT is crucial for assessing CP complications and guiding management, with AI enhancing its capabilities.

Conclusions:

  • Developing robust MRI/MRCP criteria combining ductal and parenchymal findings is beneficial.
  • Quantitative MR imaging can aid in diagnosing CP by measuring acinar cell loss.
  • Advanced imaging, including AI-enhanced CT, holds promise for improved CP evaluation.