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Breast fibromatosis: Making the case for primary vs secondary subtypes
Swapna Ghanta1, Ahkeel Allen1, Alicia Huff Vinyard1
1University of Miami Miller School of Medicine/Jackson Memorial Hospital, Miami, Florida.
The Breast Journal
|August 21, 2019
Summary
Fibromatosis of the breast, a rare and aggressive condition, is best treated with wide local excision. Achieving surgical margins greater than 1 cm is crucial for preventing recurrence in breast fibromatosis patients.
Area of Science:
- Oncology
- Surgical Pathology
Background:
- Fibromatosis of the breast is a rare, locally aggressive fibroblastic tumor.
- Diagnosis can be challenging prior to definitive surgical excision.
Purpose of the Study:
- To describe the authors' experience in treating breast fibromatosis.
- To propose a classification of primary and secondary breast fibromatosis.
- To evaluate treatment modalities and outcomes.
Main Methods:
- Single-institution retrospective analysis of 16 patients treated between 2003 and 2017.
- Review of demographic data, medical history, and treatment.
- Classification into primary (no prior ipsilateral breast surgery/radiation) and secondary (post-surgery/radiation) fibromatosis.
Main Results:
- Median age was 40 years; average lesion size was 6.37 cm.
- 14 patients underwent surgical excision with 2 recurrences; no recurrences observed with margins >1 cm.
- 7 patients had primary fibromatosis, 9 had secondary fibromatosis.
Conclusions:
- Breast fibromatosis requires a multidisciplinary approach.
- Aggressive surgical excision with margins >1 cm is recommended to minimize recurrence.
- Distinguishing between primary and secondary fibromatosis may inform treatment strategies.
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