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Correlates of successful transition in young adults with sickle cell disease

Isha Darbari1, Emily Jacobs1, Olivia Gordon1

  • 1Division of Pediatric Hematology, Department of Pediatrics, The Johns Hopkins University, Baltimore, Maryland.

Pediatric Blood & Cancer
|August 21, 2019
PubMed

Insights

Transitioning pediatric patients with sickle cell disease (SCD) to adult care is risky. Public insurance and frequent hospitalizations predict poor transition outcomes, highlighting areas for intervention.

Area of Science:

  • Hematology
  • Public Health
  • Transition Medicine

Background:

  • The transition from pediatric to adult healthcare systems poses significant risks for patients with sickle cell disease (SCD).
  • Increased mortality and morbidity are documented during this critical period.
  • Identifying factors predicting unsuccessful transitions is crucial for improving patient outcomes.

Purpose of the Study:

  • To examine risk factors associated with unsuccessful transition from pediatric to adult care for SCD patients.
  • To inform the development of targeted interventions for better transition processes.

Main Methods:

  • Retrospective analysis of patient data at a major academic medical center.
  • Statistical examination of factors correlating with transition success or failure.

Main Results:

  • Public insurance status was significantly associated with poorer transition outcomes.
  • Higher rates of prior hospitalizations correlated with unsuccessful transitions.
  • These factors identify vulnerable patient subgroups.

Conclusions:

  • Public insurance and frequent hospitalizations are key indicators of poor transition in SCD care.
  • Interventions should focus on supporting patients with these risk factors.
  • Improving the transition process can mitigate adverse health events.

Keywords:
adolescentsickle cell diseasetransitionyoung adult

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