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Acupuncture in a Rat Model of Asthma
Published on: August 25, 2020
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Is there a relationship between asthma and diabetes?
Barbara Rogala1, Andrzej Bożek2, Joanna Gluck1
1Clinical Department of Internal Disease, Allergology and Clinical Immunology, Medical University of Silesia, Katowice, Poland.
Summary
Asthma generally does not significantly impact diabetes control, except in severe cases. Low-dose inhaled corticosteroids used for asthma do not affect blood sugar levels in diabetic patients.
Area of Science:
- Endocrinology
- Pulmonology
- Clinical Medicine
Background:
- Ongoing debate exists regarding the interplay between bronchial asthma and diabetes mellitus.
- Understanding this relationship is crucial for managing patients with comorbid conditions.
Purpose of the Study:
- To evaluate the association between asthma and diabetes progression.
- To determine the effect of corticosteroid therapy for asthma on diabetes control.
Main Methods:
- Cross-sectional study involving 2431 adult patients selected from a larger cohort.
- Patients were categorized into subgroups: asthma only, asthma and diabetes, and diabetes only.
- Key parameters measured included fasting blood glucose, oral glucose tolerance, and glycated hemoglobin (HbA1c).
Main Results:
- No significant difference in HbA1c levels was observed between patients with asthma and diabetes versus those with diabetes alone (7.23±1.73% vs. 7.42±2.09%, P>0.05).
- Diabetes control criteria were met by 48.5% of patients with both conditions and 50.6% with diabetes only.
- Severe asthma demonstrated a negative correlation with diabetes control; however, low-to-mild daily doses of budesonide (≤825 mcg) did not significantly affect fasting glucose.
Conclusions:
- Asthma's impact on diabetes appears minimal, with severe asthma being a notable exception.
- Inhaled corticosteroids, when used at low or mild doses, do not adversely affect fasting blood glucose levels in patients with asthma and diabetes.
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