Related Experiment Video
Updated: Jan 20, 2026

Generation of Tissue Spheroids via a 3D Printed Stamp-Like Device
Published on: October 6, 2022
A 3D-printed portable device for field deployment of living biosensors
Paul G Movizzo1, Warren C Ruder1, Zhicheng Long1
1Department of Bioengineering, University of Pittsburgh, United States.
Abstract:
Living biosensors typically use genetically modified organisms (GMOs) to detect infectious biomarkers in clinical samples. GMOs are prohibited to be released into the environment by many laws, which limits the application of living biosensors outside laboratory settings. Here, we reported a robust 3D-printed device that eliminates the risk of exposure of GMOs to potential users and the environment. The device is designed to snugly attach to a common culture tube and consists of two components, a housing and a plunger. The housing contains a stress-focusing cutout and a reagent well to hold the living biosensor. While the plunger is designed to form a two-stage press-fit seal with the housing. The first seal allows to safely transfer the living biosensor from a biosafety lab to the field, and the second seal prevents the leakage of GMOs from the culture tube during the test and before safe disposal. Additionally, a lever-actuated machine was also designed and 3D-printed to assist users operating the device.
Related Concept Videos
Design Example: Identifying the Locations of Monuments in the Field Using Global Positioning System Device
Electric Field
In the new picture, imagine that the first charge sets up an electric field independent of all other charges in the universe. When another charge comes in its vicinity, the second charge experiences an electric force depending on the electric field at that point. The source charge does not...
Magnetic Fields
A magnetic field is defined by the force that a charged particle experiences...
Electromagnetic Fields
However, the observation of...
Field Effect Transistor
Mnemonic Devices
Acronyms
Acronyms are created by using the initial letters of a series of words to form a new word or phrase. This approach condenses complex information into a single, memorable entity. For example,...

