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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
Published on: May 16, 2025
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Mental disorders in systemic lupus erythematosus: a cohort study
Heidi Fernandez1,2, Andrea Cevallos1,2, Ruth Jimbo Sotomayor3
1Department of Internal Medicine, Eugenio Espejo Hospital, Gran Colombia Street, Quito, Pichincha, Ecuador.
Rheumatology International
|August 22, 2019
Summary
A high prevalence of mental disorders, including cognitive impairment, anxiety, and mood disorders, affects Systemic Lupus Erythematosus (SLE) patients. These conditions significantly impact quality of life, highlighting the need for integrated mental health care in SLE management.
Area of Science:
- Neuroscience
- Psychiatry
- Rheumatology
Background:
- Mental disorders significantly impact Systemic Lupus Erythematosus (SLE) morbimortality.
- Evaluating neuropsychiatric conditions is crucial for comprehensive SLE patient management.
Purpose of the Study:
- To determine the prevalence of mental disorders in SLE patients in Quito, Ecuador.
- To assess cognitive dysfunction, psychosis, anxiety, and mood disorders in this cohort.
Main Methods:
- Descriptive, cross-sectional study including 85 SLE patients (≥15 years).
- Utilized MINI International Neuropsychiatric Interview and Montreal scale for assessments.
- Analyzed associations with corticosteroid use, antiphospholipid syndrome (APS), and quality of life.
Main Results:
- 71% of SLE patients presented at least one mental disorder.
- Cognitive impairment (51%) was most frequent, followed by anxiety (41%) and mood disorders (40%).
- No statistically significant association found with corticosteroid use or APS, but mental disorders linked to quality of life.
Conclusions:
- High prevalence of neuropsychiatric syndromes in SLE patients.
- Cognitive impairment is the most common mental disorder in this SLE cohort.
- Mental health significantly influences quality of life for SLE patients.
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