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Detrusor underactivity in women: A current understanding
Siobhan M Hartigan1, W Stuart Reynolds1, Roger R Dmochowski1
1Department of Urology, Vanderbilt University Medical Center, Nashville, Tennessee.
Neurourology and Urodynamics
|August 22, 2019
Summary
Detrusor underactivity (DUA) and underactive bladder (UAB) affect many women, often requiring bladder drainage. Research is ongoing for new treatments beyond catheterization to improve management of these common conditions.
Area of Science:
- Urology
- Gynecology
- Geriatrics
Background:
- Detrusor underactivity (DUA) and underactive bladder (UAB) are increasingly recognized conditions affecting women.
- DUA impacts up to 45% of older women evaluated for lower urinary tract symptoms.
- Potential etiologies include neurogenic or myogenic dysfunction.
Purpose of the Study:
- To review the current understanding of DUA and UAB in women.
- To explore emerging management strategies and treatment options for DUA and UAB.
Main Methods:
- Literature review focusing on recent advancements.
- Specific emphasis on new management strategies and treatments for women.
Main Results:
- Current DUA management primarily relies on bladder drainage, with clean intermittent catheterization as the gold standard.
- Indwelling catheters and suprapubic tubes are common management tools.
- Treatment alternatives include medications, sacral neuromodulation, and the inFlow urinary prosthesis.
- Investigational therapies involve stem cells and gene therapy.
Conclusions:
- DUA may be more prevalent and undertreated in women than currently recognized.
- Further research is crucial to develop effective treatment options beyond catheterization.
- Providing diverse treatment choices is essential for improving patient care.
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