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Updated: Jan 20, 2026

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
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Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

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Low deceleration capacity is associated with higher stroke risk in patients with paroxysmal atrial fibrillation

Ying Ding1, Zhen-Yan Xu1,2, Hua-Long Liu1

  • 1Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, China.

Chinese Medical Journal
|August 22, 2019
PubMed

Insights

Lower deceleration capacity (DC) in paroxysmal atrial fibrillation (AF) patients is linked to a higher risk of stroke. This finding suggests DC may serve as a potential indicator for stroke risk assessment in AF.

Area of Science:

  • Cardiology
  • Autonomic Nervous System Function
  • Stroke Risk Assessment

Background:

  • Deceleration capacity (DC) is a marker for cardiac autonomic dysfunction.
  • Limited research exists on DC's influencing factors and stroke risk correlation in paroxysmal atrial fibrillation (AF).

Purpose of the Study:

  • To explore factors influencing abnormal DC in paroxysmal AF patients.
  • To investigate the relationship between DC and stroke risk in paroxysmal AF.

Main Methods:

  • Analyzed 24-h Holter ECG data from 259 hospitalized paroxysmal AF patients.
  • Utilized multivariable regression to identify factors associated with abnormal DC.
  • Assessed the correlation between DC and ischemic stroke risk scores (CHADS2, CHA2DS2-VASc).

Main Results:

  • A history of stroke or transient ischemic attack (TIA) was independently associated with abnormal DC (OR=2.861).
  • Patients with abnormal DC had significantly higher CHADS2 and CHA2DS2-VASc scores.
  • DC showed a negative correlation with both CHADS2 (r=-0.290) and CHA2DS2-VASc (r=-0.263) scores.

Conclusions:

  • Lower DC is strongly associated with prior stroke/TIA in paroxysmal AF.
  • Reduced DC correlates with increased stroke risk scores, indicating its potential as a stroke risk indicator.
Abstract

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