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Vulvar Silicone Granuloma.

Claudio Guerrieri, Rachel Hudacko, Eddy M Joseph

    International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists
    |August 22, 2019
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    Summary
    This summary is machine-generated.

    A case of vulvar silicone granulomas is presented, resulting from direct liquid silicone injections for cosmetic augmentation. This rare condition caused pain and swelling in the labia majora.

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    Area of Science:

    • Dermatology
    • Pathology

    Background:

    • Cosmetic procedures involving non-medical grade liquid silicone injections are increasingly reported.
    • Complications can arise from the migration or direct effects of these injected substances.

    Observation:

    • A 51-year-old female presented with vulvar pain and enlarged, indurated labia majora.
    • The patient had a history of bilateral labial cosmetic augmentation with liquid silicone injected in a non-medical setting.

    Findings:

    • Surgical removal of labial masses revealed silicone granulomas.
    • Histopathology showed fibrous tissue with silicone vacuoles surrounded by macrophages and giant cells, indicating a foreign body reaction.

    Implications:

    • This case highlights the risks of non-medical grade silicone injections, specifically the development of vulvar silicone granulomas.
    • Direct injection into the labia, unlike distant migration, can lead to localized granulomatous inflammation and tissue distortion.