Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ionic Radii03:10

Ionic Radii

33.3K
Ionic radius is the measure used to describe the size of an ion. A cation always has fewer electrons and the same number of protons as the parent atom; it is smaller than the atom from which it is derived. For example, the covalent radius of an aluminum atom (1s22s22p63s23p1) is 118 pm, whereas the ionic radius of an Al3+ (1s22s22p6) is 68 pm. As electrons are removed from the outer valence shell, the remaining core electrons occupying smaller shells experience a greater effective nuclear...
33.3K
Ionic Bonds00:42

Ionic Bonds

129.1K
Overview
When atoms gain or lose electrons to achieve a more stable electron configuration they form ions. Ionic bonds are electrostatic attractions between ions with opposite charges. Ionic compounds are rigid and brittle when solid and may dissociate into their constituent ions in water. Covalent compounds, by contrast, remain intact unless a chemical reaction breaks them.
Opposing Charges Hold Ions Together in Ionic Compounds
Ionic bonds are reversible electrostatic interactions between ions...
129.1K
Molecular and Ionic Solids02:54

Molecular and Ionic Solids

19.9K
Crystalline solids are divided into four types: molecular, ionic, metallic, and covalent network based on the type of constituent units and their interparticle interactions.
Molecular Solids
Molecular crystalline solids, such as ice, sucrose (table sugar), and iodine, are solids that are composed of neutral molecules as their constituent units. These molecules are held together by weak intermolecular forces such as London dispersion forces, dipole-dipole interactions, or hydrogen bonds, which...
19.9K
Solubility of Ionic Compounds02:55

Solubility of Ionic Compounds

68.0K
Solubility is the measure of the maximum amount of solute that can be dissolved in a given quantity of solvent at a given temperature and pressure. Solubility is usually measured in molarity (M) or moles per liter (mol/L). A compound is termed soluble if it dissolves in water.
68.0K
Ionic Crystal Structures02:42

Ionic Crystal Structures

16.9K
Ionic crystals consist of two or more different kinds of ions that usually have different sizes. The packing of these ions into a crystal structure is more complex than the packing of metal atoms that are the same size.
Most monatomic ions behave as charged spheres, and their attraction for ions of opposite charge is the same in every direction. Consequently, stable structures for ionic compounds result (1) when ions of one charge are surrounded by as many ions as possible of the opposite...
16.9K
Ionic Compounds: Formulas and Nomenclature03:34

Ionic Compounds: Formulas and Nomenclature

86.1K
An element composed of atoms that readily lose electrons (a metal) can react with an element composed of atoms that readily gain electrons (a nonmetal) to produce ions through complete electron transfer. The compound formed by this transfer is stabilized by the electrostatic attractions (ionic bonds) between the oppositely charged ions.
86.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Effects of electroacupuncture at "Neiguan" (PC 6) on p38 MAPK signaling pathway in rats with cardiac hypertrophy].

Zhongguo zhen jiu = Chinese acupuncture & moxibustion·2012
Same author

Accurate measurement of oxygen consumption in children undergoing cardiac catheterization.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions·2012
Same author

Glutathione S-transferase polymorphisms and bone tumor risk in China.

Asian Pacific journal of cancer prevention : APJCP·2012
Same author

Systemic oxygen transport derived by using continuous measured oxygen consumption after the Norwood procedure-an interim review.

Interactive cardiovascular and thoracic surgery·2012
Same author

Discovery and optimization of 2,4-diaminoquinazoline derivatives as a new class of potent dengue virus inhibitors.

Journal of medicinal chemistry·2012
Same author

β(3)-Adrenoceptor Antagonist SR59230A Attenuates the Imbalance of Systemic and Myocardial Oxygen Transport Induced by Dopamine in Newborn Lambs.

Clinical Medicine Insights. Cardiology·2012
Same journal

Incoming US science academy chief vows to 'double down' on research.

Nature·2026
Same journal

Author Correction: Synthesis of enantioenriched atropisomers by biocatalytic deracemization.

Nature·2026
Same journal

Electrodeposited self-assembled molecules for perovskite photovoltaics.

Nature·2026
Same journal

Neutrino's nursery found: the 'Shadow Blaster'.

Nature·2026
Same journal

Dementia risk in middle-aged people linked to a blood protein.

Nature·2026
Same journal

Daily briefing: What's really happening with trust in science.

Nature·2026
See all related articles

Related Experiment Video

Updated: Jan 20, 2026

Digital Microfluidics for Automated Proteomic Processing
10:55

Digital Microfluidics for Automated Proteomic Processing

Published on: November 6, 2009

13.0K

Ionic-surfactant-mediated electro-dewetting for digital microfluidics.

Jia Li1, Noel S Ha2,3, Tingyi 'Leo' Liu1,4,5

  • 1Mechanical and Aerospace Engineering Department, University of California, Los Angeles (UCLA), Los Angeles, CA, USA.

Nature
|August 23, 2019
PubMed
Summary
This summary is machine-generated.

This study introduces electrodewetting, a novel method for digital microfluidics that uses low voltages to move liquid droplets by causing them to dewet from a surface, unlike traditional electrowetting. This offers a simpler, more reliable microfluidic platform.

More Related Videos

Extraction and Characterization of Surfactants from Atmospheric Aerosols
09:34

Extraction and Characterization of Surfactants from Atmospheric Aerosols

Published on: April 21, 2017

17.3K
Electrowetting-based Digital Microfluidics Platform for Automated Enzyme-linked Immunosorbent Assay
08:22

Electrowetting-based Digital Microfluidics Platform for Automated Enzyme-linked Immunosorbent Assay

Published on: February 23, 2020

10.2K

Related Experiment Videos

Last Updated: Jan 20, 2026

Digital Microfluidics for Automated Proteomic Processing
10:55

Digital Microfluidics for Automated Proteomic Processing

Published on: November 6, 2009

13.0K
Extraction and Characterization of Surfactants from Atmospheric Aerosols
09:34

Extraction and Characterization of Surfactants from Atmospheric Aerosols

Published on: April 21, 2017

17.3K
Electrowetting-based Digital Microfluidics Platform for Automated Enzyme-linked Immunosorbent Assay
08:22

Electrowetting-based Digital Microfluidics Platform for Automated Enzyme-linked Immunosorbent Assay

Published on: February 23, 2020

10.2K

Area of Science:

  • Microfluidics
  • Surface Science
  • Materials Science

Background:

  • Digital microfluidics enables droplet manipulation via electric signals for various applications.
  • Electrowetting-on-dielectric (EWOD) is the primary actuation method, requiring high voltages (approx. 100 V) and specialized coatings.
  • EWOD faces reliability issues like dielectric breakdown, electric charging, and biofouling.

Purpose of the Study:

  • To demonstrate a new droplet manipulation mechanism using electrical signals.
  • To achieve droplet control without relying on electrowetting-on-dielectric (EWOD).
  • To establish a simpler and more reliable microfluidic platform.

Main Methods:

  • Developed an electrodewetting mechanism utilizing a hydrophilic conductive substrate without additional layers.
  • Employed electrical signals to induce liquid dewetting, contrasting with electrowetting.
  • Investigated the field-induced attachment and detachment of ionic surfactants to the substrate.

Main Results:

  • Successfully demonstrated droplet manipulation using electrodewetting on doped silicon wafers in air.
  • Achieved all basic digital microfluidic operations with low driving voltages (±2.5 V) and minimal current (microamperes).
  • Showcased the system's capability to handle water, common buffers, and organic solvents with low ionic surfactant concentrations.

Conclusions:

  • Electrodewetting offers a fundamentally different and potentially more robust approach to electrical droplet manipulation.
  • The low voltage and simple setup promise a versatile and reliable microfluidic platform.
  • This method could significantly advance applications in diagnostics, optics, and electronics.