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Updated: Jan 20, 2026

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WT1 regulates cyclin A1 expression in K562 cells.

Sony Pandey1, Mustafa Moazam2, Nirmala Ghimirey1

  • 1Department of Biological Sciences, Kent State University, Kent, OH 44242, USA.

Oncology Reports
|August 23, 2019
PubMed
Summary

Wilms tumor 1 (WT1) and cyclin A1 (CCNA1) are overexpressed in leukemia. This study shows WT1 directly activates CCNA1 expression, suggesting their role in leukemia progression and potential as therapeutic targets.

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