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Related Concept Videos

Patient-centered Care01:13

Patient-centered Care

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Patient-centered care involves delivering care beyond inpatient hospitalization. Reflective practice can enhance a patient-centered approach. Reflective practice is a process of reasoning that considers all aspects of the present situation, including practicalities, learning from personal practice, and consideration of patient needs. Patients appreciate care decisions made while considering their input. Involving the patient in their care provides the patient with a sense of contribution rather...
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Lattice Centering and Coordination Number02:33

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The structure of a crystalline solid, whether a metal or not, is best described by considering its simplest repeating unit, which is referred to as its unit cell. The unit cell consists of lattice points that represent the locations of atoms or ions. The entire structure then consists of this unit cell repeating in three dimensions. The three different types of unit cells present in the cubic lattice are illustrated in Figure 1.
Types of Unit Cells
Imagine taking a large number of identical...
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Center of Gravity00:58

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The center of gravity (COG) of an object is the point where the object's total weight is considered to be concentrated. Knowing the location of the center of gravity is useful when predicting the behavior of a moving object or designing static structures. In a uniform gravitational field, the center of gravity is similar to the center of mass (COM); yet, these two points can be positioned differently. For example, the Moon's center of mass lies very close to its geometric center, but...
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Center of Gravity01:15

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The center of gravity is the point at which an object's weight appears to be concentrated and can be used to balance the object perfectly. This point is essential in mechanics as it provides information regarding a body's stability and moments of inertia. The center of gravity does not always have to fall within the shape or boundaries of the body; it may also lie outside the body in certain cases.
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Predicting Reaction Outcomes02:24

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Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...
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Center of Mass00:59

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The center of mass is the point at which the total mass of an object can be said to be concentrated. It is a fundamental principle in mechanics and physics that applies to all objects regardless of their shape or size. The center of gravity is the point at which an object’s weight appears to be concentrated and can be used to balance the object perfectly.
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Using Learning Outcome Measures to assess Doctoral Nursing Education
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How different is research done by the Patient-centered Outcomes Research Institute, and what difference does it make?

Bryan R Luce1,2,3, Jason C Simeone2

  • 1Comparative Health Outcomes, Policy and Economics (CHOICE), School of Pharmacy, University of Washington, Seattle, WA 98195, USA.

Journal of Comparative Effectiveness Research
|August 23, 2019
PubMed
Summary

Patient-centered Outcomes Research Institute (PCORI) funded research uniquely focuses on patient-centered outcomes and real-world settings compared to NIH and AHRQ. This aligns with PCORI

Keywords:
AHRQNIHPCORIcomparative effectivenessinterventionalobservationaloutcomes researchpatient-centerednessreal-world evidenceresearch portfolio

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Area of Science:

  • Health Services Research
  • Comparative Effectiveness Research
  • Patient-Centered Outcomes Research

Background:

  • The Patient-centered Outcomes Research Institute (PCORI) was established to fund research prioritizing patient needs.
  • Understanding PCORI's research portfolio is crucial for assessing its alignment with its founding principles and its distinctiveness among major funders.
  • Key US funders include the National Institutes of Health (NIH) and the Agency for Healthcare Research and Quality (AHRQ).

Purpose of the Study:

  • To evaluate if research funded by PCORI aligns with its core mission and differentiates itself from studies supported by NIH and AHRQ.
  • To compare the patient-centeredness and real-world applicability of research funded by PCORI, NIH, and AHRQ.

Main Methods:

  • A comparative analysis of funded projects from PCORI, NIH (Phase IV), and AHRQ (ARRA-funded comparative effectiveness research) between 2014 and 2018.
  • Evaluation criteria included the number and patient-centeredness of outcomes (survival, function, symptoms, quality of life) and the conduct of research in real-world settings.
  • Data sources were PCORI portfolio data and ClinicalTrials.gov.

Main Results:

  • PCORI studies featured a higher mean number of outcomes (≥9) compared to NIH (≥3) and AHRQ (5.5).
  • A significantly greater percentage of outcomes in PCORI studies were patient-centered (>85%) versus AHRQ (50%) and NIH (≤30%).
  • The majority of PCORI studies (≥74%) were conducted in real-world settings, a characteristic not identifiable in NIH/AHRQ studies.

Conclusions:

  • PCORI-funded research demonstrates unique characteristics, particularly in its emphasis on patient-centered outcomes and real-world application.
  • These findings suggest PCORI's research portfolio is consistent with its legislative mandate to prioritize patient-centeredness.
  • PCORI's distinct approach differentiates it from major funders like NIH and AHRQ in comparative effectiveness research.