Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Roles of Bacteria and Fungi in Plant Nutrition02:11

The Roles of Bacteria and Fungi in Plant Nutrition

47.0K
Plants have the impressive ability to create their own food through photosynthesis. However, plants often require assistance from organisms in the soil to acquire the nutrients they need to function correctly. Both bacteria and fungi have evolved symbiotic relationships with plants that help the species to thrive in a wide variety of environments.
47.0K
Sex-linked Disorders01:43

Sex-linked Disorders

108.4K
Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
108.4K
Dose-Response Relationship: Selectivity and Specificity01:25

Dose-Response Relationship: Selectivity and Specificity

9.6K
Drugs exert their therapeutic effects by interacting with receptors, enzymes, or ion channels that are present throughout the human body. The strength and duration of the interaction between a drug and its target receptor are characterized by the selectivity and specificity of the drug. Selectivity refers to a drug's strong preference for its intended target over other targets. For instance, isoprenaline, a non-selective β-adrenergic agonist, interacts with both β1- and...
9.6K
Parentral Nutrition: Centeral and Peripheral Parental Nutrition01:27

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

795
Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
795
Microbial Nutrition01:28

Microbial Nutrition

1.1K
Organisms exhibit remarkable metabolic diversity, categorized based on how they acquire energy and carbon. These strategies enable survival in various ecological niches and are essential for maintaining energy flow and nutrient cycling within ecosystems.Energy and Carbon SourcesOrganisms are classified as phototrophs or chemotrophs based on energy acquisition. Phototrophs use light as their energy source, while chemotrophs rely on oxidizing chemical compounds. Further differentiation arises...
1.1K
Key Elements for Plant Nutrition02:35

Key Elements for Plant Nutrition

24.0K
Like all living organisms, plants require organic and inorganic nutrients to survive, reproduce, grow and maintain homeostasis. To identify nutrients that are essential for plant functioning, researchers have leveraged a technique called hydroponics. In hydroponic culture systems, plants are grown—without soil—in water-based solutions containing nutrients. At least 17 nutrients have been identified as essential elements required by plants. Plants acquire these elements from the...
24.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mating-dependent lifespan cost of sterol depletion in male <i>Drosophila melanogaster</i>.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Climate-associated natural selection in the human mitochondrial genome.

Molecular biology and evolution·2026
Same author

Disentangling the reproductive and metabolic transcriptional responses to diet in Drosophila melanogaster.

G3 (Bethesda, Md.)·2026
Same author

Mitonuclear interactions and early-life diet shape adult nutritional behaviour.

Journal of evolutionary biology·2025
Same author

Footprints of Worldwide Adaptation in Structured Populations of Drosophila melanogaster Through the Expanded DEST 2.0 Genomic Resource.

Molecular biology and evolution·2025
Same author

The metabolic costs of meiotic drive.

Proceedings. Biological sciences·2025
Same journal

Non-canonical amino acid incorporation enables minimally disruptive labeling of stress granule and TDP-43 proteinopathy.

eLife·2026
Same journal

Analysis of dendritic input currents during place field dynamics.

eLife·2026
Same journal

TopoMetry systematically learns and evaluates the latent geometry of single-cell data.

eLife·2026
Same journal

Navigating the path: Advice to physician-scientists on choosing a clinical specialty.

eLife·2026
Same journal

Neural activity profiles reveal overlapping, intermingled subpopulations spanning area borders in mouse sensorimotor cortex.

eLife·2026
Same journal

The exquisite mechanics of a tsetse bite.

eLife·2026
See all related articles

Related Experiment Video

Updated: Jan 20, 2026

Cell-Specific Paired Interrogation of the Mouse Ovarian Epigenome and Transcriptome
12:25

Cell-Specific Paired Interrogation of the Mouse Ovarian Epigenome and Transcriptome

Published on: February 24, 2023

1.2K

Sex-specific transcriptomic responses to changes in the nutritional environment.

M Florencia Camus1, Matthew Dw Piper2, Max Reuter1

  • 1Research Department of Genetics, Evolution and Environment, University College London, London, United Kingdom.

Elife
|August 23, 2019
PubMed
Summary
This summary is machine-generated.

Male and female fruit flies have different dietary needs for reproduction. Molecular mechanisms reveal opposing gene regulation in response to diet, particularly in reproductive genes, suggesting a reversed nutrient-sensing pathway.

Keywords:
D. melanogasterRNASeqevolutionary biologygene expressiongeneticsgenomicsnutritionreproductionsex differences

More Related Videos

Accurate and Phenol Free DNA Sexing of Day 30 Porcine Embryos by PCR
10:16

Accurate and Phenol Free DNA Sexing of Day 30 Porcine Embryos by PCR

Published on: February 14, 2016

10.4K
Author Spotlight: Exploring Sex-Specific Glial Signatures and Therapeutic Leads for Alzheimer&#39;s Disease
04:22

Author Spotlight: Exploring Sex-Specific Glial Signatures and Therapeutic Leads for Alzheimer's Disease

Published on: May 20, 2024

1.3K

Related Experiment Videos

Last Updated: Jan 20, 2026

Cell-Specific Paired Interrogation of the Mouse Ovarian Epigenome and Transcriptome
12:25

Cell-Specific Paired Interrogation of the Mouse Ovarian Epigenome and Transcriptome

Published on: February 24, 2023

1.2K
Accurate and Phenol Free DNA Sexing of Day 30 Porcine Embryos by PCR
10:16

Accurate and Phenol Free DNA Sexing of Day 30 Porcine Embryos by PCR

Published on: February 14, 2016

10.4K
Author Spotlight: Exploring Sex-Specific Glial Signatures and Therapeutic Leads for Alzheimer&#39;s Disease
04:22

Author Spotlight: Exploring Sex-Specific Glial Signatures and Therapeutic Leads for Alzheimer's Disease

Published on: May 20, 2024

1.3K

Area of Science:

  • Molecular Biology
  • Genetics
  • Nutritional Science

Background:

  • Sexual reproduction involves distinct male and female strategies, necessitating sex-specific nutritional requirements for optimal fitness.
  • Understanding the molecular basis of sex-specific dietary responses is crucial for explaining fitness maximization.

Purpose of the Study:

  • To investigate the molecular mechanisms underlying sex-specific gene expression in response to dietary variation in *Drosophila melanogaster*.
  • To identify shared and divergent gene regulation patterns between males and females on sex-optimal diets.

Main Methods:

  • Gene expression analysis in male and female *Drosophila melanogaster*.
  • Comparison of gene expression profiles on carbohydrate-rich (male-optimal) and protein-rich (female-optimal) diets.
  • Analysis of regulatory networks, including the Insulin/IGF-1 signaling (IIS) and Target of Rapamycin (TOR) pathways.

Main Results:

  • A core set of metabolic genes showed concordant regulation in both sexes in response to dietary changes.
  • Smaller gene sets exhibited divergent and opposing regulation between sexes, notably reproductive genes.
  • Reproductive genes were over-expressed on each sex's optimal diet, indicating sex-specific responses.

Conclusions:

  • Nutrient sensing pathways exhibit reversed regulation in males and females, leading to opposing diet-dependent control of reproduction.
  • The Insulin/IGF-1 signaling (IIS) and Target of Rapamycin (TOR) network is implicated in this reversed regulation.
  • Sex-specific dietary responses are molecularly distinct and crucial for reproductive fitness.