Related Experiment Video

Updated: Jan 20, 2026

Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages
06:04

Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages

Published on: March 24, 2023

770

Lessons From an Analysis of Newborn Hearing Screening Data for Children With Cochlear Implants

Jeon Mi Lee1, Hyun Jin Lee2, Jinsei Jung3

  • 1Department of Otorhinolaryngology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang.

Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [And] European Academy of Otology and Neurotology
|August 23, 2019
PubMed

Insights

Newborn hearing screening (NHS) can miss hearing loss, leading to delayed cochlear implants (CIs) and lower language development, especially with SLC26A4 mutations. Genetic testing and parent counseling are crucial for early intervention.

Area of Science:

  • Audiology
  • Genetics
  • Pediatrics

Background:

  • Newborn hearing screening (NHS) aims for early detection of hearing loss.
  • Limitations exist in current NHS protocols, potentially leading to delayed diagnosis and intervention.
  • Genetic factors, such as SLC26A4 mutations, are significant causes of congenital hearing loss.

Purpose of the Study:

  • To identify limitations in current newborn hearing screening (NHS) programs.
  • To provide recommendations for improved NHS protocols.
  • To analyze the impact of NHS results on cochlear implant (CI) outcomes and language development.

Main Methods:

  • Retrospective analysis of 185 children who received cochlear implants (CIs) at ≤5 years of age.
  • Review of NHS data, screening tools, age of diagnosis, hearing thresholds, causes of hearing loss, age of CI insertion, audiogram findings, and language development.
  • Statistical comparison between children who passed NHS and those referred for further evaluation.

Main Results:

  • 22% of children passed NHS, but 78% were later diagnosed with hearing loss.
  • Children who passed NHS had hearing loss confirmed significantly later than referred children.
  • The NHS-pass group received CIs later, and those with SLC26A4 mutations showed significantly lower language development.

Conclusions:

  • Parents require thorough counseling on NHS results, emphasizing that a negative screen does not preclude later-onset hearing loss.
  • Genetic testing for SLC26A4 mutations is recommended in regions with high prevalence.
  • Improved NHS protocols and genetic screening can enhance early intervention for hearing loss.
Abstract

More Related Videos

Electrically Evoked Stapedius Reflex Measurements in Cochlear Implantation and Its Application in the Postoperative Fitting Process07:00

Electrically Evoked Stapedius Reflex Measurements in Cochlear Implantation and Its Application in the Postoperative Fitting Process

Published on: June 21, 2024

1.5K
Neonatal Murine Cochlear Explant Technique as an In Vitro Screening Tool in Hearing Research08:30

Neonatal Murine Cochlear Explant Technique as an In Vitro Screening Tool in Hearing Research

Published on: June 8, 2017

18.6K

Related Concept Videos

Hearing01:31

Hearing

When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
56.6K
Analysis of Population Pharmacokinetic Data01:12

Analysis of Population Pharmacokinetic Data

Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
687
Overview of Microsoft Excel as a Data Analysis Tool01:13

Overview of Microsoft Excel as a Data Analysis Tool

Microsoft Excel is a cornerstone tool for data analysis and statistical operations, offering a wide array of functionalities to manage, analyze, and visualize data efficiently. Recognized for its versatility, Excel facilitates the performance of basic to complex statistical operations, serving as an indispensable asset for analysts, researchers, and students alike. Excel's significance in data analysis emanates from its spreadsheet environment, where data can be organized in rows and...
1.5K
Statistical Software for Data Analysis and Clinical Trials01:12

Statistical Software for Data Analysis and Clinical Trials

Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...
1.4K
Performing a Simple Data Analysis using MS-Excel Function01:17

Performing a Simple Data Analysis using MS-Excel Function

Microsoft Excel offers a suite of functions and tools ideal for statistical analysis, making it accessible to students and researchers. This article outlines fundamental Excel functions pivotal for data analysis.
SUM: This function calculates the total sum of a range of values. It's the foundation for aggregating data, essential for determining overall trends and totals in datasets.
AVERAGE: It computes the mean value of a given set of numbers, providing a quick insight into the central...
924
Model-Independent Approaches for Pharmacokinetic Data: Noncompartmental Analysis00:59

Model-Independent Approaches for Pharmacokinetic Data: Noncompartmental Analysis

Noncompartmental analyses offer an alternative method for describing drug pharmacokinetics without relying on a specific compartmental model. In this approach, the drug's pharmacokinetics are assumed to be linear, with the terminal phase log-linear. This assumption allows for simplified analysis and interpretation of the drug's behavior in the body.
One important characteristic of noncompartmental analyses is that drug exposure increases proportionally with increasing doses. This...
323