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Updated: Jan 20, 2026

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research
Published on: November 3, 2023
Renal replacement therapy for acute kidney injury in intensive care
Thomas W Davies1, Marlies Ostermann2, Edward Gilbert-Kawai3
1ACCS Anaesthesia Speciality Trainee, Department of Critical Care, University College Hospital, London NW1 2BU.
Abstract:
Acute kidney injury is a common occurrence on the intensive care unit and is associated with incremental risk of death and chronic kidney disease. Renal replacement therapy has become an essential tool in the intensive care management of patients with severe acute kidney injury and its use is rising. A basic understanding of renal replacement therapy is essential for all doctors treating acutely unwell patients. This article provides a brief overview of the principles and important considerations for the provision of renal replacement therapy for critically ill patients with acute kidney injury.
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