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Related Concept Videos

Principles of Disease Surveillance01:26

Principles of Disease Surveillance

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Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
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Leaky Scanning02:28

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During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R...
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Immune surveillance is an integral part of the innate immune system, involving the continuous monitoring of peripheral tissues to detect and respond to pathogens, infected cells, or cancerous cells. This surveillance is conducted primarily by natural killer (NK) cells and phagocytes, which employ distinct but complementary mechanisms to identify and eliminate threats.
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Scanning Electron Microscopy01:07

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A scanning electron microscope (SEM) is used to study the surface features of a sample by using an electron beam that scans the sample surface in a two-dimensional manner. Typically, areas between ~1 centimeter to 5 micrometers in width can be imaged. SEM can be used to image bacteria, viruses, tissues as well as larger samples like insects. Conventional SEM gives a magnification ranging from 20X to 30,000X and spatial resolution of 50 to 100 nanometers.
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Polarography is a classical voltammetric technique used to analyze electrochemical reactions. This method applies a linear potential sweep to a dropping mercury electrode (DME), and the resulting current is measured. A dropping mercury electrode is commonly used as the working electrode in polarography. It consists of a capillary tube filled with mercury, where the tiny droplet forms at the tip. This droplet continuously drops from the capillary, creating a new electrode surface for each...
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Radiological Investigation II: MRI and Ventilation Perfusion Scan01:30

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Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
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Updated: Jan 20, 2026

Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma
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Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma

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Surveillance scanning in lymphoma.

Sarah C Rutherford1

  • 1Meyer Cancer Center, New York-Presbyterian/Weill Cornell Medicine, New York, New York.

Clinical Advances in Hematology & Oncology : H&O
|August 23, 2019
PubMed
Summary

Surveillance imaging after lymphoma treatment shows no survival benefit for common types like Hodgkin lymphoma. Its utility is questionable for peripheral T-cell and mantle cell lymphomas, raising concerns about patient anxiety and costs.

Area of Science:

  • Oncology
  • Radiology
  • Hematology

Background:

  • The role of imaging in lymphoma management is established for baseline, treatment, and post-treatment monitoring.
  • Surveillance imaging after complete remission remains controversial despite extensive research.

Purpose of the Study:

  • To review the current literature on follow-up imaging strategies in lymphoma patients.
  • To evaluate the utility of surveillance imaging across different lymphoma subtypes.

Main Methods:

  • Review of existing studies on follow-up computed tomography, positron emission tomography, and magnetic resonance imaging in lymphoma.
  • Analysis of data regarding survival impact, patient anxiety, secondary cancers, and healthcare costs.

Main Results:

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  • Robust data do not support survival benefits from surveillance imaging in Hodgkin lymphoma, diffuse large B-cell lymphoma, or follicular lymphoma.
  • The utility of imaging in peripheral T-cell lymphoma and mantle cell lymphoma post-remission is poorly investigated and questioned.
  • Significant concerns exist regarding patient anxiety, secondary cancer risk, and healthcare costs associated with serial imaging.

Conclusions:

  • Current surveillance imaging strategies after complete lymphoma remission lack proven survival benefits for major subtypes.
  • Further investigation is needed for peripheral T-cell lymphoma and mantle cell lymphoma, with current evidence questioning routine scanning.
  • Novel monitoring methods like circulating tumor DNA detection may offer more accurate patient surveillance in the future.