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Published on: May 21, 2019
The embryonic origin of periodic color patterns
Nicolas Haupaix1, Marie Manceau1
1Center for Interdisciplinary Research in Biology, CNRS UMR7040, INSERM U1050, Collège de France and Paris Sciences et Lettres University, France.
Vertebrate coat patterns like spots and stripes are explained by a combination of developmental instructions and self-organization. Early cues establish orientation, while later processes refine pattern details and variation.
Area of Science:
- Developmental Biology
- Evolutionary Biology
- Genetics
Background:
- Periodic color patterns (spots, stripes) in vertebrates are key models for studying pattern formation.
- Two main theories exist: instructional signaling (pre-programmed information) and self-organization (spontaneous tissue acquisition).
Purpose of the Study:
- To review recent empirical evidence supporting both instructional signaling and self-organization in vertebrate pattern formation.
- To synthesize findings from studies on natural populations of mammals, birds, and fish.
Main Methods:
- Review of recent empirical evidence from molecular techniques and functional approaches.
- Analysis of studies on natural vertebrate populations with diverse periodic patterns.
Main Results:
- Evidence supports a combined role for instructional signaling and self-organization in pattern development.
- Early developmental landmarks provide foundational orientation and reproducibility.
- Later self-organizing processes shape periodicity and natural variation in patterns.
Conclusions:
- Vertebrate pattern formation is a complex interplay of instruction and self-organization.
- This dual mechanism explains both conserved features and species-specific variations in coat patterns.
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