Related Experiment Video
Updated: Jan 20, 2026

Author Spotlight: Tackling Challenges in Synthetic Cell Engineering
Published on: April 12, 2024
Construction of Disease Similarity Networks Using Concept Embedding and Ontology
Duo Helen Wei1, Tian Kang2, Harold Alan Pincus3,4
1Department of Computer Science, School of Business, Stockton University, Galloway, New Jersey, USA.
Abstract:
Discovering disease similarities are beneficial for the diagnosis and treatment of mental diseases. In this research, we proposed a data driven method, that is, integrating a variety of publicly available data resources including Unified Medical Language System (UMLS) Metathesaurus, Systematized Nomenclature of Medicine - Clinical Terms (SNOMED CT) and cui2vec concept embedding to construct a mental disease similarity network. The resulting mental disease similarity network offered a new view for navigating and investigating disease relations; it also revealed popular mental disease in the literature in terms of the number of connections and similarities with other diseases. It shows that depressive disorder is directly connected with nine other popular diseases and connects 52 other diseases in the network. The top three popular mental diseases are depressive disorder, dysthymia (now known as persistent depressive disorder), and neurosis. Future research will focus on studying the clusters generated from the similarity network.
Related Concept Videos
Causes of Similarity-Dissimilarity Effect
Self-Concept
Infancy and Emerging Recognition
During infancy, self-concept is virtually nonexistent. Babies do not distinguish themselves as separate entities and often mistake their...
Factors Influencing Attraction III: Similarity
Concepts and Prototypes
The brain organizes this information using concepts, which are mental categories grouping linguistic data,...
Formula Mass and Mole Concepts of Compounds
Protein Networks
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...

