Management of Conduction Disturbances Associated With Transcatheter Aortic Valve Replacement: JACC Scientific Expert

Josep Rodés-Cabau1, Kenneth A Ellenbogen2, Andrew D Krahn3

  • 1Quebec Heart & Lung Institute, Laval University, Quebec City, Quebec, Canada.

Insights

Conduction disturbances remain common after transcatheter aortic valve replacement (TAVR). This expert consensus provides a needed uniform strategy for managing these frequent TAVR complications.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Electrophysiology

Background:

  • Transcatheter aortic valve replacement (TAVR) has seen significant periprocedural complication improvements.
  • Conduction disturbances persist as the most frequent complication post-TAVR.
  • Lack of consensus on managing these disturbances leads to treatment uncertainty and variable pacemaker rates.

Purpose of the Study:

  • To establish a uniform strategy for managing conduction disturbances following TAVR.
  • To provide guidance based on current data and expert consensus.

Main Methods:

  • Formulation of an expert consensus document.
  • Multidisciplinary panel including interventional cardiologists, electrophysiologists, and cardiac surgeons.
  • Review of best available data and group expertise.

Main Results:

  • Identified conduction disturbances as the most frequent TAVR complication.
  • Highlighted the lack of consensus and variability in pacemaker rates post-TAVR.
  • Developed a proposed management guide.

Conclusions:

  • There is an urgent need for a standardized approach to post-TAVR conduction disturbances.
  • This consensus document offers an initial framework for management.
  • Expert collaboration is crucial for addressing this common complication.

Related Concept Videos

The Scientific Method03:50

The Scientific Method

Chemistry is an empirical science. Scientists often pose questions to understand the chemistry in everyday life and seek answers to these questions. To achieve this, scientists follow a definitive series of steps that together make up the Scientific Method. This approach involves making observations, asking questions, building a hypothesis, conducting experiments, analyzing results, and forming a conclusion. 
65.1K
The Scientific Method01:32

The Scientific Method

The scientific method is a detailed, empirical problem-solving process used by biologists and other scientists. This iterative approach involves formulating a question based on observation, developing a testable potential explanation for the observation (called a hypothesis), making and testing predictions based on the hypothesis, and using the findings to create new hypotheses and predictions.
Generally, predictions are tested using carefully-designed experiments. Based on the outcome of these...
259.2K
Ecological Disturbance02:26

Ecological Disturbance

An ecological disturbance is a temporary disruption in the environment resulting from abiotic, biotic, or anthropogenic factors, causing a pronounced change in an ecosystem. The impact of an ecological disturbance, which can depend on its intensity, frequency, and spatial distribution, plays a significant role in shaping the species diversity within the ecosystem.
20.7K
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
452
Scientific Laws and Theories02:31

Scientific Laws and Theories

Scientific Laws
87.2K
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
406